ADT For 78 year old

[DoubleIPA]

I'm 78 years old. In May/June 2024 I had 44 sessions of IMRT. I've been on Orgovyx for one year. The ADT is really affecting me - I've gone from a very active happy life to one that is quite dreary. The main SEs are lack of energy and weakness. My urologist and RO want me on Orgovyx for at least another year. I'm looking for rationale to cut that short. Has anyone seen information regarding time on ADT taking into account life expectancy? Simply put, at 78 I don't need confidence in long term "cure" - I'm concerned about 10 or, at best, 15 years. I was Gleason 8, TC-3 and PSA 12.

[Tall_Allen]

I assume you were diagnosed with high-risk PCa. Here's the dilemma: You can take your medicine now, for one more year, or take the same medicine permanently later. Stopping too soon will guarantee that only the most resistant cancer cells survive and replicate. Those cells will cause painful and crippling metastases later, for which you will beg for the same medicine for the rest of your life. I wish you had another alternative.

[CAMPSOUPS in reply to Tall_Allen]

This comes up often and as is often the case you convey the science (the particulars of PC and treatments) perfectly as it pertains.

This reply is one of many that should be carved in stone.

Thanks again for everything you do here!

❤️❤️❤️

[Nodrogear]

Hi there. I am 84 .nine years ago I had brachytherapy to treat prostate. Showed all clear for six years then PSA rose to 12. Was treated with two doses of ADT, six months apart and PSA fell to 0.02. Was advised to continue ADT for another year but declined as the side effects were loss of libido, skin rash etc. was advised that if PSA rose again to 5.00 I could return to ADT. After four months the pSA is back at 3.10 so I will review in two months. Also had PET scan last year and was all clear. My only fear is the mastacis which may occur if I continue to do nothing! I guess the deal is around your quality of life, while you live😉

[BigAla]

What did your PSMA PET CT show?

[Nodrogear in reply to BigAla]

All clear

[DoubleIPA in reply to Nodrogear]

"Impression: Abnormal uptake in the left side of the prostate. No lymphadenopathy, bony metastatic disease of distant metastatic disease was noted."