PSA Trend

[caysary]

Hello gentlemen,

Can anyone tell me if this trend is normal or concerning. Please read my profile before reply. I am going into my 3rd year after SBRT. Nadir may have not been reached yet.

[Justfor_]

I had to guess the months, but they should be close enough.

My take: With a PSADT of ~3.3 years you shouldn't be concerned.

Nadir was in the second quarter of 2023 IMO.

Caysary

[caysary in reply to Justfor_]

Thank you Just for but how do you know nadir is reached when it can take up to 4-5 years for that.

[Justfor_ in reply to caysary]

To start with, I don't "know" what the future may bring. I am just offering you my best estimate based on the time series at hand. To take it a bit further, nadir is a mathematical quality/property, not a temporal one. The graph that you posted depicts a curve that went through a minimum. Is this the minimum minimorum, aka the nadir or not? No one, serious enough, can tell you, sorry.

[caysary in reply to Justfor_]

Appreciate that. here's a profile of a 3+4 no ADT that my give clues as to why some are different at nadir:

Nov 2017 Treatment is done 5 sessions over 2 weeks Original PSA 13

PSA Test May 2018 5.0 6 Month

Nov 2018 2.1 12 Month

Nov 2019 3.1 The is the PSA bounce at 18-24 months

Nov 2020 2.0 36 Month

Nov 2021 .46 48 Months

Nov 2022 .16 60 months

Nov 2023 .12 72 months

Apr 2024 .07 78 months

[NanoMRI]

curious about why 4 mo ADT and did you not have a PSA timeline mapped out with doc?

[caysary in reply to NanoMRI]

Good point Nano. They didn't so here I am.

[Don_1213]

Actually your profile seems a bit sketchy - not a lot of info to go on there. I did notice you've been concerned for some time with your PSA in prior posts to this group.. have you discussed this with your medical oncologist? What's he have to say about it?

[caysary in reply to Don_1213]

He is on vacation till the tenth