Study shows HIFU noninferior to prostatectomy for localized prostate cancer

[ToolBeltZia]

urologytimes.com/view/study...

[pd63]

A number of posts on this forum have shown that HIFU doesn't work, others can elaborate further.

[ToolBeltZia in reply to pd63]

Just putting the latest research out there.

[fast_eddie in reply to ToolBeltZia]

As well you should but expect to be swatted down by someone here who has taken it upon himself to viciously campaign against it.

[fast_eddie in reply to pd63]

Well I am here to show that HIFU does work. All the posts on this forum that condemn it are from one person who has no personal experience with it. I am 7 1/2 years post HIFU. I received full gland HIFU ablation at age 66. I am 74 now. My PSA has crept up to 3.4 but I've had no quality of life adverse impact. No incontinence. No impotence. Axumin scan 3 years ago: clear; no activity. Pylarify scan a year ago: clear; no activity. MRI prostate scan two weeks ago: no lesions detected. I did have TURP surgery 10 years prior to prostate cancer diagnosis. That surgery is pretty much a prerequisite for full gland HIFU. I consider focal, or partial gland HIFU to be half-assed. I think that is where most of the complaints about HIFU effectiveness derive.

[dentaltwin]

Yeah, this is gonna ruffle some feathers. I'd have rather seen BCR rather than "STFS" (salvage treatment-free survival) as the metric. Also, that 26% positive surgical margins suggests maybe the selection criteria weren't that great.

[cpl901]

it has to be focalized and done well. Hiw can one know there only one (or two) tumors. With biopsy ? No. with mri ? No.

[ToolBeltZia in reply to cpl901]

PSMA PET would likely give the best diagnosis as to the number of lesions. Perhaps an MRI perineal biopsy to start with. There is no magic bullet in PC, just choices, (hopefully) informed choices.

[fast_eddie in reply to cpl901]

Why 'focalized'? Full gland HIFU is superior.

[cpl901 in reply to fast_eddie]

I can only speek in my case : if i would have insist i coukdt have done HIFU and keep surgery for salvation , but at this point my prostate would shrink so much that would make surgery difficult. Fortunatly i choose surgery right away because they where many small focus of cancer cells even not agressive G 6 but major part was G 3+4. I just hope my psa will stay undetectable for …. 25 years. I m now 58

[fast_eddie in reply to cpl901]

I was Gleason 8 in one core, 7 in two and 6 in two. Only right side of prostate. Good luck with your treatments and recovery.

[Xavier10]

Dr. Kwon calls it “pre-treatment.” Hehe

[ToolBeltZia in reply to Xavier10]

I am not advocating, just informing.

[fast_eddie in reply to Xavier10]

Dr Kwon doesn't perform it so he has a slight bias as do many urologists who don't include it in their bag of tricks.

[NanoMRI]

Nine years ago I traveled to London, England to consult with Professor Dr Mark Emberton on HIFU. His recommendation, based on mpMRI findings, surgery. Interestingly, the referenced study makes no reference of mpMRI in considering HIFU.

[Chasbearcat999]

The “must be over 69” was odd.