PSA barely went down after surgery

[Smkb7963]

My Dad had surgery Jan 6th. Pre op psa was 8.4 and 7 weeks post op psa was 6.2. He had PET Axumin scan done last week nothing came up on it. His Dr seems shocked his psa is still so high and doesn't know why this would be. Has anyone experienced this?

[Tall_Allen]

What were his pathology results?

[Smkb7963 in reply to Tall_Allen]

It showed all clear according to dr but I read something about nodules.

[Tall_Allen in reply to Smkb7963]

What was the pathology Gleason score? He should begin whole pelvic salvage radiation with at least 6 months of ADT.

[Smkb7963 in reply to Tall_Allen]

pre op is was 8 after surgery they said 7.

[Horse12888 in reply to Tall_Allen]

TA: Don't they do scans to locate tumors before RP? I don't understand what happened here.

[Smkb7963 in reply to Horse12888]

He had a scan pre op and showed nothing according to the dr.

[Justfor_ in reply to Smkb7963]

Up to now, I have had 21 PSA tests out of which 2 were absurdely erroneous. This is a 10% error rate. Did you countercheck with a repeat test performed by a second lab?

[Smkb7963 in reply to Justfor_]

Yes the 2nd one was almost the same as the one the week prior...

[Justfor_ in reply to Smkb7963]

Was it by the same lab or a different one?

[Tall_Allen in reply to Horse12888]

Yes, but there are many false negatives. Scans are very limited in the amount of cancer they can see.

[Magnus1964]

As long as it's going down. Some of that PSA may be do to irritation from the surgery.

[Gemlin_]

A persistent PSA after radical prostatectomy can, unfortunately, mean cancer has progressed and metastasized. A secondary treatment is then hormone therapy.

[garyi in reply to Gemlin_]

The exception, rather than the rule.

[fluffyfur]

Did he have any nodes removed during surgery? If so how many and was cancer found in those?

[j-o-h-n]

Greetings,

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j-o-h-n Sunday 03/14/2021 6:31 PM DST