PIRADS3 and biopsy?: MRI PIRADS3 I am... - Prostate Cancer N...

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PIRADS3 and biopsy?

bartesam profile image
28 Replies

MRI PIRADS3

I am 60.Working as a . DDS, Very good health and lifestyle. No family history with PC at all.Asymptotic but 5,7 PSA. PSAD 15, All normal ultrasound and no findings with urologist exam.

Did a lot of hard bodybuilding exercise weeks before the PSA. Also use of slender tone electric belt muscle stimulator. About 60-90 minutes daily on max power.

Well , I put that away, ???

Just had MRI

No typical tumor findings. PIRADS 3 Perrier zone, possible prostatittis related findings, but is very unclear.

If PSA stays high, he advice urologist exam for possible need of further examination.

I had the urologist exam the day after, and no clinical findings. All normal.

Well, after researching I am not to interested in Biopsy at this time, but observations.

Any comments?

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bartesam
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28 Replies
Tall_Allen profile image
Tall_Allen

Suggest you get a Prostate Health Inventory (PHI) test instead of PSA next time. It includes PSA, but also measures other biomarkers that are less influenced by prostatitis and BPH. I think you meant your PSAD is 1.5, not 15.

bartesam profile image
bartesam in reply to Tall_Allen

Sorry, PSAD is 0.15

bartesam profile image
bartesam in reply to Tall_Allen

Thanks. Never hard about PHI.

GabF profile image
GabF in reply to Tall_Allen

Beware that PHI has no signifiance outside a narrow PSA range: 2-10 ng/ml (for FDA it is: 4-10). Here it France, it costed me 96€ (US$ 117), and was useless PSA at 1.3 or 1.77.

Tall_Allen profile image
Tall_Allen in reply to GabF

Bartesam's PSA is 5.7

bartesam profile image
bartesam in reply to Tall_Allen

4,5 now.PSAD 0.12. So next check will be in August. URO sounded happy.

Tall_Allen profile image
Tall_Allen in reply to bartesam

Were you able to get PHI?

bartesam profile image
bartesam in reply to Tall_Allen

I believe serum was shipped to Radium hospital in Oslo, not received any results.

LowT profile image
LowT

Measure free PSA

LowT profile image
LowT in reply to LowT

What was prostate size on MRI?

bartesam profile image
bartesam in reply to LowT

37

LowT profile image
LowT in reply to bartesam

Has a free PSA been done?

bartesam profile image
bartesam in reply to LowT

No

Darryl profile image
DarrylPartner

This video provides a helpful discussion about PIRADS. youtu.be/MITXIAPLEaU

bartesam profile image
bartesam in reply to Darryl

Thanks. I am following the program. Watched it yesterday,

maley2711 profile image
maley2711

Generally, it is advised to have a biopsy of a PIRADS 3. 10-20% of PIRADS 3 biopsies find significant cancers...but your call...maybe you're comfortable with that low probability? My PIRADS 3 as graded by Kaiser was just later regraded by a med school radiologist to a PIRADS 5...80% probability of significant cancer!! You could ask for an MRI 2nd opinion from a highly recognized prostate radiologist?

bartesam profile image
bartesam in reply to maley2711

Thank you. Yes , I understand the possibility is about 8% , according to one of the lectures presented theses last days.

The radiologist I believe is highly recognized, but my dentist friend has a good friend , a radiologist who performs second opionions, and I guess he will have a look.

The radiologist wrote in his report the following .

R: No tumor typical findings . The finding could be related to prostatittis changes but the finding is doubtful.

And than he wrote.

In case of PSA still being high , urologist exam is advised, to see if there is further indication for diagnostic exam.

So I get a little confused. So, if the PSA dropped I would not need to go for the urologist exam???

Anyway I did the urologist exam the same day, as I received the MRI report.

No symptoms , no urinate problems, nothing on prostate palpation or on the ultrasound.

So far, I am thinking of new blood tests in some weeks.

I found my old PSA test just know.

2015. PSA. 0,8

I don’t know if my hard exercise, electric belt stimulation in the lower stomach area, off road bicycle activity, and DHEA medication weeks before the PSA test, could have any effect.

maley2711 profile image
maley2711 in reply to bartesam

Oddest report i've yet seen!! Prostate MRI readings require hi level of expertise.......MHO. a specialty.

bartesam profile image
bartesam

Not strange I belive the same. Strange. And not possible to talk to him to clearly.

aceace12 profile image
aceace12

not sure why you would not consider biopsy.. it is true indicator .... i would get second reading on MRI ... if PSA stays high get the biopsy have it also read by John Hopkins......... good luck

bartesam profile image
bartesam

I got confused by the report. And believe I will do the biopsy if the PSA stay high or rises. I hear there is much pain doing the biopsy and if there is no sign of tumor on the MRI like he writes, why not wait, do a new MRI next year, and avoid the risk of infection doing the biopsy. A friend of mine did one last weekend got hospitalized. Than again, he also mentioned PIRADES 3. ...

tsim profile image
tsim

Show this to your urologist and ask if he can go to the lab and see if they can dial in the Larmor frequency for citrate on their spectro magnet

ncbi.nlm.nih.gov/pmc/articl...

Garp41 profile image
Garp41

Bart,

You could send your MRI to Dr, Walser in Galveston, Dr.Karamanian in Houston, or Dr. Feller in Palm Springs, CA., for a 2nd, 3rd opinion.

I have heard 4K Score and Select MDX are good urine tests to help decide on a biopsy. I had the 4K.

Best,

Doug

Justfor_ profile image
Justfor_

Avodart is claimed to reduce the PSA count by taking out of the total the benign component. It takes time for it though. Two or more years for a 50 percent reduction. You could take it for 2 to 3 months and see if you get a lower PSA count and by how much

Kevin1957 profile image
Kevin1957

My PSA went up almost 3 points (3 to 5.5) from running 3 miles the day before. All your results are borderline,,,Pirads 3, PSAD 15%, and slightly elevated PSA. I think I would take it easy for several days, meaning no sex, exercise of any kind and repeat the PSA. Was the 0.8 PSA reading in 2015 the last one you had before the 8.7?

bartesam profile image
bartesam

Yes, 2015, PSA 0.8

2020 PSA. 6

Two weeks later , 5,7

Had stopped using the electric stimulation stomach training belt for 3 days, and stopped taking Dhea tablets for 3 days.

Used the electric stimulation for about 90 minutes daily for many weeks.

The pad was placed in the belt area, and like 10 cm tissue from prostate.

Powerful contractions in the area.

Mufj profile image
Mufj

All youre results are borderline and withoit a recent psa trend it is hatrd to make judgement. Continue to monitor psa, get phi or 4k test. If you have an upward trend in psa or if above test show probability of cancer then get biopsy. I would do psa every 3 mo for more data. Getting 2nd or third opinion on mri is goodFor me biopsy was no big deal but infection is risk. You should get antibiotics when getting biopsy.

Best of luck

GabF profile image
GabF

I feel, like you, that biopsy is a very old method and not an easy one for monitoring cancer. I thought that, with so many new advances in medicine, it would have been new means to monitor cancer. So I refused biopsy, for taking time to find out other means. I found PHI and I used it twice. But for me, it was useless because my PSA is too low, out of the signifiance range. I also used every suggestion I found in this forum (LDH, ...). But I understood that comparing two MRIs could be enough for me. Of cource no physician acknowlege it could be used for diagnostic. I understand that very well: they have biopsy which is accurate around 90%, why take the risk to switch to another mean which is accurate at 70% ? But that is physcians' problem, not mine. They can't take any risk, I can take some. So I insisted in having a second MRI after 3 months of "naturel treatments". Big success: my second MRI was read by the best specialist here (Paris), and she saw no cancer, one lesion but very unlikely cancer. She suggested me to have biopsy nine months later, and a systematic one; or a third MRI.

So PC is slowly vanishing from my thoughts; I go on with my treatments but lightened, in sequence and no more in parallel.

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