hi. My blood labs show my CRP was 9.4 in June. I had pain and increased my prednisone to 3mg. My pain stopped snd Ive been feeling great. Now my Labs todsu in August show a further increase in CRP to 19. My ESR is normal at 12. I dont understand why as Im feeling good and tnought my CRP should be down. Im so devestated and depressed by this. Its been 5 years now and I never have had this happen. Can anyone give me some guidance and advice?
Thank you in advance.
Sometimes anxiety itself will cause a rise in CRP, or an infection, lack of exercise, poor diet, eg. foods high in carbohydrates, not drinking enough water. If my CRP rose without explanation I would speak to my doctor/rheumatologist for reassurance.
As 123-go has said anxiety , amongst many other things may cause an increase in inflammation markers.
Mine have been raised a couple of times once when my late husband was very ill [I did still have GCA at that time but no flare whatsoever] - and again a few years later [GCA in remission ] but following a couple of replacement surgeries, 6 months apart.
But would also say, if CRP is raised but ESR isn’t it could just be a glitch, an issue at the laboratory or similar. So get it retested and see what that is. A one-off out of sync result should be reviewed.
thanks for your advice - will def retest in a fee weeks and see.
Other things can raise it besides PMR. What does your doctor say/think?
I havent spoken to my doctor yet and my next appt with rheumy is in October. Was wondering if having fallen and having a very bad bruise on my hip could have done it? As well had a mild case of food poisoning several days ago. Wonder if that could make it go up?
Both could, especially if the muscles were badly bruised in the fall or even others wrenched as CRP is also a muscle enzyme. CRP is seen to be highest about Day3 after a poisoning event and then falls again - does that fit?
I think this is likely what happened. Im going to repeat my bloodwork in a few weeks and see.
It was just rather depressing seeing the lab work result. Ive been also dealing with a lot as my adult daughter who struggkes eith anorexia is discharged from hospital and still struggling. I am a grsndmother and helped to raise my grandchild , and well life has been not easy. However there has been a lot of good too so Im not complaining but stress probably is a factor in why I ever became sick and maybe even now - who knows? I just go day to day. But thank you for the help. Its hard when you feel alone with this disease.
Thank you!
Stress will raise CRP and ESR - and you are stressed.
I have a very high CRP all the time. The highest was 412 and the lowest 29. The doctors have decided it is just me after various tests.
That is very interesting. Something to remember.
My only worry is the doctors may be wrong!!
Yes I know. it is not easy this disease - it always has twists and turns and ups and downs. Its a wild ride I never wanted! My best to you that all is well with you!
ESR & CRP Update
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CRP levels 
What if I have normal ESR and CRP?
