Toc and covid vaccine : For the life of me I can’t... - PMRGCAuk

PMRGCAuk

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Toc and covid vaccine

Devoid profile image
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For the life of me I can’t think what I’ve done previously??. Had covid vaccine on Thursday having injected on Monday, is it beneficial to hold off this Mondays dose?

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PMRpro profile image
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wmic.wales.nhs.uk/wp-conten...

says

"No specific timing issues found. For patients receiving intravenous tocilizumab, suggest scheduling vaccination at any time but leave a 7-day gap before the next treatment. For patients receiving weekly subcutaneous tocilizumab suggest scheduling vaccination midpoint between the last and next dose"

and this

link.springer.com/article/1...

says

"Vaccines and tocilizumab

TCZ is a humanized monoclonal IL-6 receptor blocker and is generally used for the treatment of diseases such as rheumatoid arthritis and large vessel vasculitis. It is also one of the main choices of cytokine storm treatment that may develop in the course of COVID-19 [60]. Mori et al. showed that TCZ treatment did not prevent the development of antibodies against the influenza vaccine in RA patients [61]. Recently, in another study evaluating the humoral immune response of the polysaccharide pneumococcal vaccine in RA patients receiving TCZ, no difference was observed between TCZ recipients and the control groups [62, 63]."

Not sure how the first helps since the response usually takes 7-10 days. Personally, I'd miss the next s/c jab but it doesn't seem to matter greatly. Rituximab is the really problematic one.

Devoid profile image
Devoid in reply to PMRpro

Thanks again you really are amazing and 100%more reliable than the nhs advice line x

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