Pred three times a day

[Mayadill]

I did this with an open mind, being my own guinea-pig, bearing in mind the other bits I’ve picked up: preempting the IL-6 dawn chorus and the less Pred in the body the better coming up to midnight.

I was thinking along the lines of some dose-times in some people create a kind of yo-yo every 24-hour cycle, from no Pred to masses of it, depending on how long it takes your body to get through a dose – is that necessarily useful if the time of lowest/no Pred comes way away from the witching hour.

Previous experiments: all of it at 2 am, but feeling distinctly less than wonderful 23 hours later when got up to get a snack to take it with, and also murdered sleep and the same with the dose split in 2 – I never got around to buying those empty EC capsules.

Therefore somewhere between half past midnight and 2 am, 5 mg; on surfacing say 10-ish 3 mg; around 4 or 5 pm 1 mg. It is actually working rather well, so well I have twice nearly forgotten to take the tabs.

Also, the 2 am dose has stopped screwing up my sleep, which seems to me to be broadly in line with the higher the dose of Pred and the closer it’s taken to bedtime the more likely it is to disturb sleep - presumably 5 mg as opposed to the earlier attempt at 7 mg at 2 am is low enough for my sleep to survive.

[PMRpro Ambassador]

Did you try 2x daily - which can also be timed so you don't have to take a 2am dose.

[Mayadill in reply to PMRpro]

Yes. 1 or 2 am isn't in itself a problem to me. Waking at 5 or 6 was. This has now stopped and I sleep through.

[PMRpro Ambassador in reply to Mayadill]

You can fiddle wth timings to not need to wake ar silly times at all.

[Mayadill in reply to PMRpro]

Not waking, world's worst owl. When young and fit could cheerfully bounce through to 4, now moderated.

pink owl under the moon

[LIVEORDIEHEREIAM]

I am doing something very like you are. Currently at 7.5 MG. The 2-ish AM dose is no problem because my bladder is reliably going to wake me about then anyway. Skipping a daytime dose is a possible problem, but I mostly have those set as part of a mealtime "ritual". Works for me with the same benefits you mention. Nice to know that there is someone else in the same boat!

[LemonZest11]

As we say in Australia, you're an ideas woman! What ever works, but I just couldn't handle the hassle of taking 3 doses. The old 2am with yoghurt trick, suggested here by Pro and DL, saved me. Good luck to you!