I discovered Metoprolol may cause arthralgia- myalgia

[sdowney717]

the-rheumatologist.org/arti...

I decided to not take that beta-blocker anymore. I still will take Amlodipine and Lisinopril and may ask to go on carvedilol again and still have a bunch of carvedilol pills I can take. It was after I was switched to metoprolol that I started getting PMR symptoms. Period of time for me between beginning Metoprolol and PMR was about 6 months. One thing the article notes is within a few days of stopping Metoprolol, that women's joint pains went away.

I also had to go back to 10mg and 5mg prednisone cause after steadily dropping to 5 and 5, I could not shake off the knee pain even going to 7.5 and 5. I just made that change a day and a half ago. And I am pain free in my knees. But still experience smallish transitory morning stiffness and pains also in the wrists. Will stay here for a week or so, then drop again to 7.5 and 5 prednisone. How many of you are aware that metoprolol can cause bad joint pains?

The article says her " Pain was migratory", and so is mine, pain moves around, comes and goes. Sometimes wrists, one other both, one or both knees or no knee pains. I also can have some jaw pain - stiffness and a finger pain that gets worse and better, same middle long finger on both hands. The finger pain happened months before any PMR symptoms for me. Those pains come and go. I have not felt much or any shoulder or hip pain since starting prednisone, and even big reductions in prednisone never brought those back. 2 weeks into starting prednisone at 20mg after PMR diagnosis, knee pains came on strong enough could hardly walk and that knee pain seems to randomly come and go away completely.

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[nallufl24]

I didn’t know about the joint pain but Metoprolol made me feel terrible. I kept getting chest pain. I also felt depressed. Every time I got on the scale I gained another pound. I started taking Carvedilol and felt normal again

[PMRpro Ambassador]

Not dissing the drug effect - but what you are describing is also typical of an inflammatory arthritis called palindromic rheumatism which can be misdiagnosed as PMR. There is a member on the forum who finally was diagnosed with it.

[sdowney717 in reply to PMRpro]

My PMR diagnosis was made by noting my CRP was 103. My xrays showed no arthritis. My ANA was negative, RF test negative. Severe fairly quick onset pain in both shoulders and both hips. I first started feeling slight PMR type pains in late November 2022, and they steadily grew worse till I was about incapacitated. Then I sought out some medical help in late Feb 2023. Prednisone knocked out that pain in less than 2 days. Interesting about the palindromic disease process.

Can also be possible a person can have multiple similar disease processes ongoing at the same time.

[Boss302Fan]

Which did you take Metoprolol succinate er or Metoprolol tartrate? I’ve been on the former since before and after PMR and no manifested negative side effects.

[sdowney717 in reply to Boss302Fan]

Metoprolol succinate 50mg. I still have zero knee, wrist, jaw pains after stopping it. I also dropped my am prednisone again to 7.5 from 10.

[sdowney717]

No terrible knee pains since quitting Metoprolol, no odd joint pains at all. MY GP when I mentioned the terrible knee pain coming and going randomly claimed was OA, or RA developing, wanted an Xray, and did not even think that it is one of the side effects of that drug. His only solution idea was knee injections of steroids, which I naturally and wisely refused.

I knew I had no OA in my knees. My knee joints are as smooth as melted butter. it was always inflammation of joint tissue like PMR, not physical joint destruction.