Those of us on 40 mg and higher, or even lower Pred. What mg are you taking for the Proton Pump Inhibitors (PPI's) I take 20 mg of Omeprozale by once a day. Wondering if I should take (one am) and (one pm)
PPI's: Those of us on 40 mg and higher, or even... - PMRGCAuk
Better probably means it last longer and us a little more available. I would always choose an extra mg of pred to 40 or 80mg of ppi. But i was on ppi for almost 18 yrs as it was standard prescription for diabetes. I suspect only my excess weight stopped potential bone thinning.
I take both coated and uncoated.. 5mg coated on a night so it starts to work for morning and 2.5mg uncoated in the morning.
Of course you are on higher dose so might want to just keep tapering if you are happy and 🤞 it's not GCA.
Wish I knew if it was or wasn't....no way of knowing now. Hope second blood test is back in the morning to enable me to tell rheumy when he calls me at 11 am Will be interesting to see what he tells me when to start tapering. I told him that I'd joined the Forum, he was impressed. However, I can't say to him that I'm taking advice from members and not him, but I will ha ha !!
It was based on a study done in patients with a GI condition, Crohns I think, where it would almost certainly affect how it was absorbed lower down the GU tract. It doesn't really matter how much is absorbed for us as we are titrating the dose to find the ideal dose for us personally. People absorb anything between 50 and 90% of the oral dose anyway so titration in something like PMR/GCA is essential to make sure that each patient has the correct dose.
Do you feel you actually need it? I certainly wouldn’t just in case because of the potential side effects which includes bone thinning. As Poopa’ says, try asking for coated Pred. That’s what I did because PPI’s made me feel peculiar and caused intestinal upset. When the doc said it was more expensive I pointed out that the lack of PPI prescription meant it wasn’t and occasional bit of nightly Gaviscon I needed I bought myself.
Hard to know what to do then. I was told to take them but X 2 daily...I've only been taking one. Every drug we take has to go through our livers, so possible liver damage too over time. Even BP med cause some people side affects that are not nice. Still trying to decide whether to take the Alendronic Acid.....do wish I'd been able to have the Dexa scan...blasted Virus !!
40 mg...only seems after taking the Calcium though. I'll google that too I think...things we can learn on here. If we're taking different drugs, eg Alendronic, Calcium, Steroids and Calcium how would we know which one is affecting us. If we told our rheumys and GP's about this we'd get laughed at and told not to read about it them.
I had lots of side effects while taking a PPI. They caused more stomach problems than the Prednisone. I switched to Pepcid AC and it made all the difference in the world. Usually just need twenty mgs at noon but take another 20mg at night if needed. It’s expensive just like PPIs but my Doctor writes a prescription for the generic famotidine and it’s much cheaper. It’s helped so much I can go days without taking it.
I have been taking Omeprazole 20mg since last April. I took famotidine for 2 years before that, but it stopped working. Coated prednisone is not available in the US, for reasons I can’t understand. I hate being on omeprazole, as it affects my lower GI tract. I have developed diverticulitis (3 episodes since May) since I started it. If I had the choice I would be taking coated tablets.
I was told by private hospital pharmacist that the un-coated Pred absorb better then the coated ones. I just think they want us to take them just to protect our stomachs, like Alendronic Acid to protect our bones.....whether we end up taking any of these drugs is entirely up to us I guess. Still contemplating whether to take the Alendronic, really don't want to. To be told by my rheumy that if I had a fracture it could kill me does cause for concern.
Everyone has to decide what works best for themselves. For me, I would do whatever I could to avoid omeprazole, but I can’t. I don’t have any bone thinning (I’ve had the test) so I don’t need AA, thankfully. Fortunately I only have PMR, but I can’t get my prednisone dose down enough to avoid side effects. All these drugs have risks and benefits, and everyone is different, so it’s definitely individual.