CAN PMR be reason for a resistant HBP.: I am... - PMRGCAuk

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CAN PMR be reason for a resistant HBP.

SRIXON profile image
10 Replies

I am struggling with high blood pressure, after taking my 3 tablets in a morning for hi BP im ok for approx 6 to 8 hours with BP around 135/85, it then starts to rise late afternoon to around 170/98.

Last 3 months Ive had three tablet changes but to know avail.

Can my PMR have any infkuence to my resistance to BP MEDS.

I am on 3 mg steadily coming down which is good as im type 2 although im not good in the morning with stiff/ache shoulders, upper arms and wrist. Carl x

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SRIXON profile image
SRIXON
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10 Replies
SheffieldJane profile image
SheffieldJane

There does seem some difficulty in finding a BP medication that suits us. Atenolol gives me approximately 150- 55 over 90. My GP says that it’s a “ rubbish” drug for BP. This is a pity because I have no side effects. I felt deathly sick on some modern one they tried. My BP is steroid induced I believe, but I am only on 4 mgs.

SRIXON profile image
SRIXON in reply toSheffieldJane

Hi Jane, thanks for responding. I have been on Ramapil & Filodipine for some time now but due to Bp wanted to introduce a third. Ist was tox-----, this made me anxious, dizzy, 2nd Indapamide which did improve my BP but gave me other issues. Im now on Spironolactone which is proving after 1 week to be useless.

Im down to 3 mg on my pred putting up with stiff shoulders and upper arms, pay back is my sugar level is much more controlled, sadly BP isnt, I understand your body can build up a resistance to BP tablets.

My High BP was caused as a result of the Prednisolone, it took four attempts to get the right BP Meds for me. Apparently, it is difficult to get just the right Meds to treat hypertension so you may just have to persevere.

Good Luck 🍀

Hope they can find something to suit you soon.

MrsN

Ciar profile image
Ciar

I came down with high BP last spring after 2 years on prednisone. I was taking 5 mg. My doc put me on Nadolol (did nothing) then tried adding lisinopril(still nothing). Stopped that, tried Losartan which works but had to be reduced due to side effects. Then she tried to add a diuretic and I just couldn’t stand the idea of 3 more drugs in addition to the 4 I was already taking. I wound up taking a little less losartan and Nadolol. This worked for 7 months but now BP is creeping up sporadically. So frustrating! Seems like resistant BP to me. I don’t want to add a third drug.

PMRpro profile image
PMRproAmbassador in reply toCiar

There are some positive points to multiple but low dose medications in HBP - the combined effect is good but the adverse effects are less.

Ciar profile image
Ciar in reply toPMRpro

Thanks PMRpro. At least there could be some good in it. I’m just so tired of taking so many drugs. And still my health is getting worse month after month.

PMRpro profile image
PMRproAmbassador in reply toCiar

I do know the feeling - being handed methotrexate and folic acid almost reduced me to tears! But since then I have actually been taken off one of the BP meds as well!

Reader7 profile image
Reader7

Frustrating, isn't it? I just started my fourth medication for HBP...it's finally coming down. I've done everything I can lifestyle-wise...daily exercise, low-salt diet, meditation, maintaining a normal weight, low stress. I'm just glad the right combination was finally found...I'll gladly pop the pills!

I know the pred has a role to play but pain can shoot BP up too. I had been on diuretics for years then the year before I was dx, but showing symptoms, my BP was very high. I tested at home a few times at 200 over 101 which got me to Dr's pronto. By the time I got to see the dr it was 150s/90s. I was put on linisopril but it still fluctuated, added amlopidine and I felt like I was dying. Went back on linsinopril alone and it settled. My blood pressure has been better on pred but seems to fluctuate with flares. Sounds counterintuitive but perhaps you should increase pred by 1mg and see if stiffness goes. In terms of hba1c 4mg should be fine. Then you can see what effect symptoms have on your BP.

PMRpro profile image
PMRproAmbassador

If PMR is due to large vessel vascilitis that is making the artery walls swollen and the lumen of the vessel narrower that will lead to raised BP. Some people do find that their BP falls after starting on an adequate dose of pred to manage their symptoms because the vessel walls are less swollen.

Pred can also lead to raised BP because it leads to retention of sodium which also causes fluid retention - more fluid in the same size system raises the pressure inside the vessels. In this case careful use of diuretics may deal with the hypertension - but if you are still on pred you do need to be on the right sort and your electrolyte levels should be monitored (sodium and potassium).

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