Documentation: Everything I post is 100% backed... - PMRGCAuk

PMRGCAuk

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Documentation

Boss302Fan profile image
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Everything I post is 100% backed either by published research (I also take account of the date of the publication), consult with my GP or Rheumy, what I’ve experienced directly, or what “I’m” doing. With the later sometimes it contradicts what my doctor is telling me (e.g., my GP wants me to stop taking the mixed Tocols (forms of Vitamin E) and Vitamin K2).

Going forward if I state something specific that’s not an opinion I will post the title of the paper along with a link (with a direct reference to the page and paragraph). If there’s a way to upload as a pdf, I’ll do that too.

As a disclaimer I am not, in any way, associated with any medical profession, nor have I any medical degrees. The decisions I make are for me alone and the info I provide is a FYI that possibly may help others. Remember, everyone is different and what works for me, may not work for you.😀

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Boss302Fan profile image
Boss302Fan
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SheffieldJane profile image
SheffieldJane

I think that goes for most of the regular contributors on here. Thanks for the reminder.

Jan_Noack profile image
Jan_Noack

I take vie Mixed tocopherols and micxed tocotrinols as well as the alpha VitE, and it K2..also from reseacrh. I'm still unsure , as I take 100mg aspirin a day too how the K2 and aspirin go(I'm at very high risk of a stroke)..but one hospital emergency dept doc said its fine as they work by entirely different mechanisms (he was a student studying it I guess)?..so if anyone has any knwoledge of this from research..like what happens when you mix vitK2 and aspirin..does it still thin the blood? I also drink loads of water..which is the most important for stopping clots than anything. at least 12 glasses per day..(probably less if in Uk in winter though)

PMRpro profile image
PMRproAmbassador in reply toJan_Noack

Vit K2 is less involved in bleeding than vit K1 - I assume that is what you are meaning when you ask about aspirin being involved? I assume that aspirin is the preferred option for reducing the form of stroke you are at risk of having? I am on a few medications that relate to increased risk of bleeding but with other forms of anticoagulant therapy the vit K story is less significant.

Jan_Noack profile image
Jan_Noack in reply toPMRpro

Thanks PMRPro. Yes, I have up to 60% blockage from plaque on an ultrsound of left carotid, bout 30% on right carotid arery. I assume this want helped by the narrowing at top of carotid from moyamoya which is almost closed (I think)on the left..hence the blood flow slowing I guess. I have natural hghest cholesterol but no one was too concerned as my HDL was also very high making the ratios good...obviously this is incorrect advice. I tried Lipitor but felt bad and my liver enzymes went up. Now on crestor..feeling better (except for the smoke knocking me last few days). The smoke cleared mostly last night with the long-overdue rain. High risk of stroke from moyamoya, hence needing a brain op (STA-MCA or EC_IC, and I do not even know if they are the same). But before the brain op I thought I neded a nagigram..but one neurosurgeon told me he didn't mention a scan to me as I was at too high a risk of stroke from it dislodging or even, I think, roughening the plaque. I think he planning on operating without any angiogram, he wrote he felt it was not necessary. I have two neurosurgeons, two it seems disputing schools here in Sydney (seems an ongoing fight over the funding, setup and patients for clot removal from 2016..still ongoing).

i definitely feel a load better on aspirin, and the vitK2 is as I have severe osterporosis..and to help stop any calcium deposit into the plaque, to stop it breaking up and causing a stroke..at least that's the thougt. I've also upped my water level to over 12 cups a day which is about what I used to take. This always helps. I find it diffucult to work out what is moyamoya and what is PMR, but the ultrsound showed up the plaque, but good new is I do NOT have GCA and I have clear STA :)

Jan_Noack profile image
Jan_Noack in reply toJan_Noack

I was scheduled for the angiogram on last Friday (2 days ago) and called by hospital afternoon before abut i thought I had postponed it..very tempted to go ahead but the interventional radiologist had not contacted me and my GP wanted me to ask him if he could just go up to the plaque and then inject the dye (iodine ) from there. The hosputal staffwanted me just to show and ask him on the spot but I really can't tell him what to do which is almost what tht would be! He never returned my call either, but I found an email from his secretary that night saying not to go.

Boss302Fan profile image
Boss302Fan in reply toJan_Noack

Here is another excellent publication regarding K2... what bothers me somewhat is where they mention 49 “mg” dosage pertaining to effective dosage for bone replacement (if I read it correctly. I need to read it again and follow the reference trail). Later they speak to the order of magnitude lower doses I’m used to reading.

The Emerging Role of Vitamin K2

Manouchehr Saljoughian, PharmD, PhD

Department of Pharmacy,

Alta Bates Summit Medical Center,

Berkeley, California

uspharmacist.com/article/th...

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