Liver: Anyone have decreased liver function on... - PMRGCAuk

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Liver

Libertylane profile image
7 Replies

Anyone have decreased liver function on prednisone. What do you do ? Is there alternate drug that doesn’t cause this? So many questions from me.

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Libertylane profile image
Libertylane
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7 Replies
PMRpro profile image
PMRproAmbassador

Why would pred cause decreased liver function? The recommendation is that anyone who has liver problems may be better put onto prednisolone than prednisone as prednisone must be processed by the liver to make prednisolone which is the active substance and may not be reliable.

Bird-67 profile image
Bird-67 in reply to PMRpro

Now that is interesting, will mention it when I see the Rheumatologist next week.

Bird-67 profile image
Bird-67

Yes I do but my GP and my Rheumatologist has never connected it to the Steroids and think it might be because I had Shingles recently.

SheffieldJane profile image
SheffieldJane

Are you looking at the internet and worrying yourself to a frazzle? If so, give it up for a bit and talk to us instead. Or has your doctor expressed concerns about one of your blood tests? The liver is a resilient organ that can actually repair itself well, if I remember correctly. Most drugs and alcohol put an extra strain on the organ. Large doses of Pred are not great but they are temporary. Perhaps you should talk to your GP about your anxiety levels. Having experienced health anxiety myself, I think I recognise it in you. Apologies if I am mistaken.

Libertylane profile image
Libertylane in reply to SheffieldJane

No you are right about anxiety. I have had some abnormal liver blood work in recent tests numbers just above. Check my symptoms as they come. Have been treated by doctors for anxiety and was almost off all meds before this. Thanks for replying

PMRpro profile image
PMRproAmbassador in reply to Libertylane

Some liver function tests are raised in untreated PMR.

Lanakay profile image
Lanakay

After a couple of blood tests with not normal liver results my doctor ordered an ultrasound of my liver. Now he has said I have a fatty liver. He says they will just keep an eye on it.

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