when awake in the early hours….An interesting tak... - PMRGCAuk

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when awake in the early hours….An interesting take on cortisol which I came upon whilst browsing

Teekay2 profile image
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when awake in the early hours….

journal of reflections by Meng-hu, resident of the Hermitary

Diurnal rhythm by Meng-Hu

From health and psychology magazines to medical journals, the topic of cortisol is well-covered, if not outright popular. The function of the hormone cortisol is to increase standard defenses of the body, to serve as the body’s alarm system, as the website WebMD puts it. These defenses are raised when perceived stress assaults the body, physically or psychologically, increasing heart rate and blood pressure, regulating inflammation and blood glucose, and other mechanisms for providing the impetus to “fight or flight.”

What most commentators neglect is that the cortisol function often serves as a dysfunctional hijack of otherwise normal bodily functions. The organs directed by the flow of cortisol are the most primitive in the human body: hypothalamus, pituitary, and adrenal. The cortisol function is a remnant of evolution that modern humans do not require for survival. A primitive Paleolithic hunter might need an alert system to gauge whether to fight or flee from a rampaging woolly mammoth. In primitive times cortisol serves a survival function, and marshals the energy needed to execute whichever decision the person elected: to fight or to flee.

But if the historical stressors no longer exist, the body stills responds as if they do. Such overreactions can create hypertension, heart rate concerns, disruption of hormones, and potential damage to organs that such conditions can precipitate. As if the cortisol hijack is not enough concern, modern stressors have come to replace outdated ones. Stress from domestic relations, jobs, commuting, children, neighbors, debts, living conditions, hostility, safety concerns, the daily news — the list can go on. Yet modern stress sources replace ancient stress sources, and multiply them in number and intensity. Further, we cannot fight or flee. These are not options in modern society. The cumulative effect of numerous stressors essentially points to the backdrop of modern existence. And yet the cycle of cortisol continues, unabated by the profound changes of civilization.

If we further identify the cycle of cortisol in the body, the diurnal rhythm, we observe that during sleep the levels of cortisol are minimal, and that they begin to rise around 4 AM and peak at 8 AM. The emergence of cortisol in this pattern suggests that ideally cortisol benignly awakes one with a gentle nudge not at all related to “fight or flight.” It is a natural biorhythm following the course of the dawn, the emergence of light, a natural cycle renewed every day.

Indeed, monastic traditions East and West historically adopted for its adherents a schedule of prayer and meditation that begins about 4 AM and concludes at 8 AM. This is no coincidence but an unspoken, perhaps intuited, insight. Such a universal tradition is addressing the need to capture the cortisol cycle, assign it a practical function, and engage it for as long as practical. Thus the practice of four hours of prayer or meditation at the beginning of the day addresses the power of cortisol, harmonizes its effects, and harnesses the cycle for good.

In the West, the monastic tradition of observing ritual hours of the day (Matins, Lauds, Prime, Terce, Sext, None, Vespers, and Compline) served physiologically to absorb the imprint of all hours, all occasions of fight or flight, superseding subjective ruminations associated with given hours of the day or night. Western traditions varied Matins to midnight or 2 AM, with the rest of the day’s schedule varying by tradition and season. In Eastern traditions, too, hours take on significance. Theravada and Zen Buddhist monks have historically maintained similar schedules, rising at 4 AM to meditate for one hour, then chanting for one hour. At 6 AM, the monks historically went out of the monastery to beg food alms in the villages, returning by 8 AM for breaking their fast, with today’s modern discretion substituting more meditation, chanting, or light work during the latter hours. Hindu monastic routine, too,is nearly identical, further incorporating the seven chakras to address physiology and metabolism into a system of understanding the self. Thus culture, geography, and environment might move the schedule slightly forward or back in winter, or establish slightly different routines within different schedules.

If these grand traditions perceived a necessity to master the cycle we now know as the cortisol cycle, and can pinpoint the time of its rise and fall, then common sense suggests that we,too, should avail ourselves of a significant time of day and make our early daytime hours parallel those of the wisdom traditions.

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Teekay2
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PMRpro profile image
PMRproAmbassador

Perhaps you could include some context as to how this is relevant to patients on corticosteroids for PMR and GCA?

Teekay2 profile image
Teekay2 in reply toPMRpro

I just thought it was interesting so shared it.

PMRpro profile image
PMRproAmbassador in reply toTeekay2

The purpose of the forum is for things relevant to living with PMR and GCA and steroids and after much turmoil in the past that is now taken as a basic principle for posts. Hence my request for some context.

Teekay2 profile image
Teekay2 in reply toPMRpro

ok

Noosat profile image
Noosat in reply toPMRpro

I believe it applies to me waking at 4a.m. ready to get up. (I make myself stay in bed until 5:30 so as not disrupt others) Also the morning is my most productive time, with lethargy in the afternoon.

SheffieldJane profile image
SheffieldJane

This is interesting and enlightening. My meditation teacher of the Brahma Kumaris tradition taught that God is always listening at 4 am and it was an excellent time to meditate. I am usually awake then but not at all stressed by it, I usually feel pretty good. Unlike my working days. 🌸

Teekay2 profile image
Teekay2 in reply toSheffieldJane

I spent some years in India in asramas and briefly in a Buddhist Monastery in Thailandand as you say the auspicious time is Brahma Muhurta an hour and half before sunrise. I love the early mornings,so peacefull.

HeronNS profile image
HeronNS in reply toTeekay2

I used to go to a Presbyterian church camp when I was a child and young teen. Every morning before breakfast we each took a little meditation booklet we'd been given and found a place by ourselves and spent I think it was ten minutes by ourselves just soaking in the quietness of the morning and using our little booklets as a guide. I still remember that experience.

HeronNS profile image
HeronNS

I think, given that almost everyone who comes down with PMR can point to a stressful event as a final trigger setting off the cascade leading to illness, anything which helps us understand how to deal with our stress responses is relevant. I learned within a couple of months of starting pred that stress would make me feel like I was going up in flames, and learned to pick my battles and avoid stress, and therefore probably some flares.

Thank you for posting.

PMRpro profile image
PMRproAmbassador in reply toHeronNS

That was the sort of thing I meant.

Teekay2 profile image
Teekay2 in reply toPMRpro

I thought the relevance was self evident. I certainly did not mean to post anything inappropriate.

PMRpro profile image
PMRproAmbassador in reply toTeekay2

The trouble is, it isn't always self-evident to everyone.

Joaclp profile image
Joaclp in reply toTeekay2

Perhaps the rest of us are here to help tease out the applications to our conditions. Certainly, the experts have talked often about the right time to take pred in order to tap into diurnal cycles. For complicated medical reasons, I was changed to hydrocortisone from prednisone and, as a result of its more "natural " status, I am very aware of my cortisol cycles. Thank you for this post offering a context of this in religious practice!! Best for the annual cycle beginning January 2020!

Noosat profile image
Noosat in reply toTeekay2

You are right.

PMRCanada profile image
PMRCanada in reply toHeronNS

I related to the post as I suffered with PTSD for years due to the nature of my work. For years I existed in an almost constant state of “fight” or “flight”, taxing my adrenal system, constantly calling for cortisol while I lived in a world of hyper-vigilance. I don’t think it was a coincidence that years of living in constant stress and distress, fearing for my safety, living through night terrors, etc, took its toll and eventually I developed PMR.

The post explained many things and it resonates with me.

Thanks for sharing Teekay2!

Louisa1840 profile image
Louisa1840

Thank you for this thoughtful & inspiring post Teekay2. I am a Christian but really open to others spiritual paths too. I meditate every morning and simply absorb the Christ (common to all spiritual paths that teach peace). I am usually awake around 4 a.m. We are told that the cytokines that cause the inflammation in PMR are most active around then. I am SO interested in a holistic approach to any illness and I think your post deserves further investigation to those who are of an open mind?

Blessings.

nuigini profile image
nuigini

I'm often up at 4 am and thoroughly enjoy the early morning hours, so the post was very interesting. I've done a fair bit of reading on the the production of cortisol as fatigue is the major reaction with each reduction in prednisone. I believe there's also a slight increase in cortisol in late afternoon. When I'm experiencing the fatigue of reduction what little energy I have is at the times mentioned.

daworm profile image
daworm

Interesting, once tapering down and adrenals kick in ..or try to kick in, understanding a bit about cortisol is even more interesting...but is there a way to stop rampant cortisol? Seems no...

PMRpro profile image
PMRproAmbassador in reply todaworm

What do you mean by "stopping rampant cortisol"?

daworm profile image
daworm in reply toPMRpro

I don’t know...sounded good though...

PMRpro profile image
PMRproAmbassador in reply todaworm

:)

The body does that under normal conditions - it all works a bit like the thermostat for the boiler on the central heating: enough cortisol means the HPA axis (hypothalamus, pituitary, adrenal glands are told there is enough available and so they don't produce more. In an emergency situation there is a need for more and it registers that too and a spike is produced to deal with the urgent requirement (illness, trauma, emotional need). Taking pred above about 8mg means the room is warm enough all the time and the adrenals get the message after some weeks they can take a holiday but that only applies for patients on above about 7mg for more than a couple of months or higher doses after a shorter time.

There is also a medical condition that results in the production of too much cortisol, Cushings disease, but that isn't the adrenals malfunctioning, it is a pituitary tumour producing too much signalling stuff, ACTH, telling the adrenals to carry on working, the thermostat has a cold draught on it, the other rooms are too warm.

So the "rampant cortisol" only applies in illness or when you are on a high dose of pred.

Nanna71 profile image
Nanna71

You lost me at 'evolution', which I don't for a second, believe is part of the human condition.

Manchild profile image
Manchild in reply toNanna71

???????

daworm profile image
daworm in reply toNanna71

Your. Hoover I guess..

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