Prednisolone 1 mg dose - which countries is it av... - PMRGCAuk

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Prednisolone 1 mg dose - which countries is it available ?

Iwillwin123 profile image
55 Replies

Hello all,

I need your help to know Whether 1mg gastric resistant prednisolone tablets available in Hong Kong or Singapore or the UK or then anywhere else in Asia .......

Regards

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Iwillwin123
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55 Replies
DorsetLady profile image
DorsetLadyPMRGCAuk volunteer

I don’t know that we have any contributors from HK, Singapore or Asia - but you could probably find out if you look at the Public Health sites for those countries you are interested in!

Why do you need to know? If you are going on holiday, most take enough medication to cover the time away.

Iwillwin123 profile image
Iwillwin123 in reply to DorsetLady

What we get is only 5 mg and 2.5 mg dosages. Now after stepping down to 10 mg all the way from 60 mg ....... slowly at rate of 2.5 mg every stepdown per 15 days, I intend to follow the DSNS method of stepdown and step down at rate of 1 mg per each stage. For this it seems I must look for a source of 1 mg prednisolone ..... hence the query .

Since I have family in Singapore, HK and UK , they will help out in sourcing it ....., again the prescription is another concern too ....... also if I could get the reliable brand names then it would be even more helpful .

SRIXON profile image
SRIXON in reply to Iwillwin123

60 mg wow respectfully say thats a high dose

Iwillwin123 profile image
Iwillwin123 in reply to SRIXON

Yes 60 mg sure is . And I cannot begin to describe the myriad challenges I faced on the way to the current stage in the step- down at 10 mg . But would want to reiterate to others in that exalted space that there is NO need for fear, everything works out well eventually and I am an example of that so far ..... and as I chose the ID “ Iwillwin” needless to say that the attitude matters in these weird health situations.

Also to reiterate again , I could never have made all the wise and smart choices I did without the guidance of all the folks here. They are way wiser than all the medical guys out there often !

Regards

PMRpro profile image
PMRproAmbassador

As far as I know it is a UK resident! I don't know of anywhere else that uses it. The manufacturer is in the NE of England and I suppose they may be able to tell you if any is exported:

piramalpharmasolutions.com/...

Why do you ask?

Iwillwin123 profile image
Iwillwin123 in reply to PMRpro

What we get is only 5 mg and 2.5 mg dosages. Now after stepping down to 10 mg all the way from 60 mg ....... slowly at rate of 2.5 mg every stepdown per 15 days, I intend to follow the DSNS method of stepdown and step down at rate of 1 mg per each stage. For this it seems I must look for a source of 1 mg prednisolone ..... hence the query .

PMRpro profile image
PMRproAmbassador in reply to Iwillwin123

Most people use 1mg plain pred to make up the dose. Alternatively you can use the Dead Slow and Nearly Stop to do 2.5mg steps but very very slowly - like doing each step at least 2 or 3 times. That is part of the reason it was developed they way it was because at that time there ws no 1mg enteric coated pred at all, it has only been around for just over 3 years.

It really would be helpful if you could complete your profile with some basic details - like at least what country you are in. I know you have told me - but that was a bit back, I can't remember and I'm not going to plough through all your posts to find it!

Iwillwin123 profile image
Iwillwin123 in reply to PMRpro

I live in India . We get prednisolone only in 5 mg and 2.5 mg doses here.

in reply to Iwillwin123

Are they coated/gastric resistant/enteric or uncoated?

Iwillwin123 profile image
Iwillwin123 in reply to

Uncoated - brand name Wysolone is what I was using so far.

PMRpro profile image
PMRproAmbassador in reply to Iwillwin123

Thought it was - but as Poops says, coated or uncoated?

Iwillwin123 profile image
Iwillwin123 in reply to PMRpro

What we get here is uncoated. Now since I was trying to source it from outside my country then I felt using gastric coated will be a better choice to have that is all .

Iwillwin123 profile image
Iwillwin123 in reply to Iwillwin123

Also please correct me if I am wrong but as I understand using DSNS method is better with 1 mg stepdown s rather than doing so with 2.5 mg stepdown s ?

in reply to Iwillwin123

Yes we do 1mg or 0.5mg. If super slow taper.

We were inquiring if you had coated or uncoated as you can cut uncoated. If you cut 5mg UNCOATED into 2 then 2 again. It is as good as 1mg. You just get a bit extra each day that is meaningless really.

I cut my uncoated 1mg pills to take 0.5mg if 1mg is too much. If I take 7.5mg I take 1 x5mg coated 1mg uncoated and 0.5mg uncoated.

Iwillwin123 profile image
Iwillwin123 in reply to

OK . I was exactly worried about cutting the pill since I was worried about non-precise cutting ,in terms of the possible variant amount of dosage. As I now understand —— it is OK to get a little bit extra - it is not a concern ......

in reply to Iwillwin123

No concern...sometimes I miss the Centreline but I haven't felt a difference.

HeronNS profile image
HeronNS in reply to Iwillwin123

This question came up a day or two ago and PMRpro wondered what these countries do when they need to have doses for children. You could enquire about that. It may mean having to take that 1 mg in liquid form but it could tide you over until you can find a reliable source of the 1 mg pills.

in reply to HeronNS

I have checked main Indian suppliers and it would be syrup for children, as they start at 5mg.

Iwillwin123 profile image
Iwillwin123 in reply to HeronNS

Yes will find out about 1 mg in liquid form . That did not occur to me. I will check and update here .

HeronNS profile image
HeronNS in reply to Iwillwin123

Please let us know what you are able to find out. It will help others in the same difficulty if you find a reasonable solution. Good luck!

Iwillwin123 profile image
Iwillwin123 in reply to HeronNS

Found out that pred is available in pediatric syrup form as 5 mg/5 ml . So now if I do not manage to lay my hands on 1 mg tablets then I will combine 5 mg pill plus the necessary additional mg doses in liquid form ———- please give me your opinion on this method. I mean I am still concerned about measuring out EXACT 1 ml / 1 mg doses as add on .

HeronNS profile image
HeronNS in reply to Iwillwin123

Check with your pharmacy about getting a dropper which will measure tiny amounts exactly. A tad daily difference one way or the other really won't matter with pred.

Iwillwin123 profile image
Iwillwin123 in reply to HeronNS

Ok . Will look at the pharmacy for such a dropper.

PMRpro profile image
PMRproAmbassador in reply to Iwillwin123

It is - but when needs must! If wishes were horses, then beggars would ride.

If you want enteric coated then you need ALL enteric coated and since the UK is the only place you can get it as far as I know you would have to go to the UK, get a prescription and source it there since no-one else can prescribe it if it isn;t in their country's system.

Anyway, if you have 2.5mg uncoated - then cut the 2.5mg tablets with a pill cutter which will give you 1.25mg steps. If you use the DSNS approach it will work with 2.5mg too, so 1.25mg is not far off 1mg.

Iwillwin123 profile image
Iwillwin123 in reply to PMRpro

Found out that pred is available in pediatric syrup form as 5 mg/5 ml . So now if I do not manage to lay my hands on 1 mg tablets then I will combine 5 mg pill plus the necessary additional mg doses in liquid form ———- please give me your opinion on this method. I mean I am still concerned about measuring out EXACT 1 ml / 1 mg doses as add on .

PMRpro profile image
PMRproAmbassador in reply to Iwillwin123

Exact isn't important. All you are doing is looking to take less than you took with the previous dose, it is immaterial if you take 0.45mg or 0.55mg less if you are cutting tablets. Same with liquid.

Personally I think you are making things complicated where it may not need to be. If you can get the liquid, use it. But liquid will be absorbed in a few minutes, plain tablets take an hour, enteric coated take up to 4-5 hours or even more.

Iwillwin123 profile image
Iwillwin123 in reply to PMRpro

Ok . Will not worry about the minor dose variance then :)

Regards

Iwillwin123 profile image
Iwillwin123 in reply to Iwillwin123

And also valuable point about the differences in absorption times noted.

Iwillwin123 profile image
Iwillwin123 in reply to PMRpro

Oh ok ...... so if I comprehend correctly - you still recommend cutting the pill and accepting a 1.25 or a 2.5 mg dose for stepdown —— rather than using a combo of pill plus pediatric syrup ....... ????

Constance13 profile image
Constance13 in reply to PMRpro

Not to do with this post but......

Are you having any difficulties in Italy?

Am having difficulty with supplies of Lodotra 2 mg here in Germany. It's the start I fear!!

PMRpro profile image
PMRproAmbassador in reply to Constance13

The start of what? It is manufactured in Germany and France - shouldn't be supply problems with that in Germany.

Constance13 profile image
Constance13 in reply to PMRpro

Can get Lodotra 2mg in only 30 tablets a time (instead of 100). As I take 2 every evening it's a pain in the backside!

PMRpro profile image
PMRproAmbassador in reply to Constance13

I have only ever got Lodotra in 30 tablet packs. Didn't know it came any other way. And I can only have 2 months worth of any particular dose at a time. I just call the GP and she sends the e-script to the pharmacy in the village.

Constance13 profile image
Constance13 in reply to PMRpro

Wow, I have had 1 mg, 2 mg and 5 mg in 100 packs all the time.

PMRpro profile image
PMRproAmbassador in reply to Constance13

I suspect it is a fairly commonly used form in Germany - mine had to be ordered every time at first but the new rheumy here obviously likes using it as there is someone else in the village who is on it, it is on the shelf now.

Sally001 profile image
Sally001

I live in British Columbia, Canada and we have prednisone in 1 mg doses.

Iwillwin123 profile image
Iwillwin123 in reply to Sally001

Thankyou . This info will help me .

Regards

Sally001 profile image
Sally001 in reply to Iwillwin123

Good luck to you Iwillwin123, hopefully your doctor can get it for you.

Iwillwin123 profile image
Iwillwin123 in reply to Sally001

Thankyou :)

Mimma profile image
Mimma

They are available in the UK. I use them.

Iwillwin123 profile image
Iwillwin123 in reply to Mimma

Are you using the brand manufactured by Alliance Pharma ? If yes then what is the name of the brand that you use. Also are there any other such brands in Suzlon making 1 mg ?

Regards

PMRpro profile image
PMRproAmbassador in reply to Iwillwin123

Only Alliance makes the enteric coated version. Many companies distribute the plain 1mg version across the world - and most will be generics simply marketed as 1mg prednisolone. You would need to use your search engine to find which companies do so or hear from everyone who uses it.

Iwillwin123 profile image
Iwillwin123 in reply to PMRpro

Yes true. Will search and must to get to the more popularly trusted names.

Iwillwin123 profile image
Iwillwin123 in reply to Iwillwin123

I always feel so grateful to have found so much solid support here. Even the doctors have often not been as uptodate , as the folks here.

Mimma profile image
Mimma in reply to Iwillwin123

Sorry missed your question.. They are Alliance prednisolone gastro resistant tablets. No other information on the packet.

aladymo profile image
aladymo

Canada disburses 1mg tablets. ( i’m not sure that will do you any good ,)

Iwillwin123 profile image
Iwillwin123 in reply to aladymo

All info is welcome and useful :) Thankyou ,

Regards

nickm001 profile image
nickm001

Live in Japan and can get plain 1mg pills. With cutter I create 0.5 mg and even 0.25mg doses. Smaller doses are useful when reducing below 3mg FYI.

Iwillwin123 profile image
Iwillwin123 in reply to nickm001

What we get is 5 mg and 2.5 mg . So that is an odd number to start stepdown by 1 mg steps ........ also I was concerned about a variant dose with a pill- cutter ...... I guess I will have to use a combo of pill plus pediatric syrup (5mg/5ml) which apparently is available. Though how to measure out accurately 1 mg is again a doubtful area for me .......

nickm001 profile image
nickm001

There was a guy here in forums that would crush the pills and then measure with very precise scale portion of the powder to create the amount he desired. Just another option, but maybe too extreme.

Iwillwin123 profile image
Iwillwin123 in reply to nickm001

Oh really ? That would require a lot of daily consistent precision over a long period of time ........ may be hard for me to replicate .......

HeronNS profile image
HeronNS in reply to Iwillwin123

You'd need some sort of fine lab equipment, too. Not worth it!

Iwillwin123 profile image
Iwillwin123 in reply to HeronNS

Agree :) Unless one is a true blue scientist at heart !

PMRpro profile image
PMRproAmbassador in reply to Iwillwin123

Not really - a true blue scientist also knows the limits of reasonableness and sense and where orders of magnitude apply ...

Iwillwin123 profile image
Iwillwin123 in reply to PMRpro

True that :)

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