I have read here the length of time of the effects of a daily dose of predisone is typically 12-36 hours. Should there be a correlation between the length of time one feels the effects (ie- symptoms are controlled) and the amount (or size) of the dose?
I had been on 10 mg for 4 months and generally felt pretty decent- enough that I really didn't track hours of comfort- and was also working full-time.
Now I am on 60 mg and effects last about 16 hours (Also on month-long vacay so lots of rest). It seems to me that the effects of a high dose SHOULD cover 24 hours; because it's not, I am concerned that might mean there is another problem.
(4 weeks ago I was bumped from 10 mg to 60 mg as reaction to ESR and CRP results- I think flare, Dr cautious of GCA; 2 weeks ago blood work came back all in normal range.)
Is aiming for 24 hrs of comfort a reasonable expectation- especially on a high dose- or is the daily rollercoaster of symptoms just the new normal? Grateful for your thoughts.