I'm back again. Sleep, or lack of it is, wearing me down. Am currently on 20mg for another 9 days and then down to 15. My problem is when to take so I can sleep. Tried splitting it, major part in morning and then lesser at night because of break through. Last night I was in kitchen eating yogurt at 1 AM and bread at 3 AM. Tired and gaining weight. What is best time to take prednisone and should I split dose? I realize fatigue is part of PMR but lack of sleep makes it worse. Thanks to all of you, I learn so much from this forum.