Hydroxychloroquin or HCQ has worked very well as an alternative to Methrotroxate for me. It is not as toxic and has no real side effects. I was struggling to reduce from 60mg. I couldn't get below 20 without a flare up. It does take about 3 to 4 weeks to fully get into the system but I have now been steadily reducing for 8 months and got down to 8mg. My only issues since taking HCQ have been bruising and muscle ache. I have found the prescription Voltarol relieves muscle pain and double base cream keeps the bruising on my arms down. I hope this post will be of help to those with similar problems.Many rheumatologists don't always suggest this alternative.