Frequency of injections with regard to healing

[Chickens44]

I have asked before about frequency of injections, but I’m wondering if frequency has a bearing on how long it takes to repair the myelin sheath? Will every day injections help to repair more quickly or are we just wasting B12. I know some people say they feel better on every day as opposed to EOD, but just wondering if it will speed up the process.

[Jillymo]

We are all different.

It depends on how long you have been deficient, what neurological damage has taken place ect.

It is a case trial and error to find what best works for you.

[JesusMercy60]

I often wonder that same question myself about the myelin sheeth. as well as the brain myelin sheeth. but I know it is working on me I see the difference but I'm not at all healed yet. My other question is once the myelin sheeth is healed do will we still have the nerve pain? I would think not but I also wonder about that.

[Treesong2023 in reply to JesusMercy60]

It all takes a long long time lovely. I believe it happens in stages. I think the B12 recovery continues over time, repairing existing nerves and cells of the damage first to allow better function, but not regenerating the damaged ones for full function for sometime. Just like a scar goes away over time....?

[Hockey_player in reply to JesusMercy60]

I stopped having nerve pain and tingly toes after starting injections.

[Wwwdot]

Hi Chickens

What a good question!

As Jillymo says we are all different so to answer your question for you, you will need to be observant of your body to give it what it needs to repair at a faster rate.

I share my experience with you. I was diagnosed in 2022 when I was 60 and my B12, folate and vitamin D were at rock bottom, my ferritin was ok but not brilliant. I had been deficient and in decline for about 20 years it turns out.

I set off on a mission to recover as much as possible in a 3 year period. No science behind that it just seemed sensible and I based it on the time it took to restore my donkeys’ health after years of severe malnutrition.

In the early days ie the first 3-4 months I was injecting ever other day but there came a point when I had a very clear good day (B12 day) and a bad day (no B12).

I noticed that on a B12 day my urine was darker and more yellow than on a no B12 day. There was a discussion about this in the forum and it was thought the urine colour could be excess B12 and/or increased toxins as the B12 works to renew cells thus getting the new cell/old cell “conveyor belt” system working again.

During this time I supplemented my cofactors and after 3 months I had a blood test and all co factors were better but still not between mid range and 75% which is what I was aiming for.

I decided to increase my B12 to ever day and I decided to increase my cofactors too so extra jab, extra cofactors. Every day was a good day and my urine was darker and more yellow every day. My B12 symptoms began to subside and I began to have more energy.

I had a further blood test around 4 months later and my cofactors were again improved but not in the target range.

To fast forward to now - all my cofactors are in the target optimal range. I had to switch to methylfolate tablets instead of folic acid as it turns out I don't methylfolate folate well. My ferritin is stubborn but is at a reasonable level but not on target. I inject 2-3 times a day and now experience virtually no neurological symptoms unless I forget to inject or I over do it. I have been able to return to work 10 months ago after being unable to work for 18 months.

What is most interesting (to me at least! ) is that my urine is light and only a slight yellow tinge even though I am injecting more so I think more B12 is being used productively and the backlog of toxins due to compromised cell renewal has been cleared.

During the time I keep notes of symptoms and observations in my body. During year 2 I focussed on healing my gut during year 3 I will focus on toxin removal and keeping the progression of my disease under control best I can.

I have abandoned the idea of trying to reduce my B12 dose on the basis that to do so is illogical if my B12 store and recycling system is broken and the expectation to reduce or exist on less is not based on research but unsupported medical expectations and what a HEALTHY FULLY FUNCTIONING BODY NEEDS- but I will stop before I get on my soap box!

Believe in yourself as you know your body best. Set yourself a safe and realistic plan and keep an eye on cofactors. As I progress and my diet has improved my diet is now the main source of vitamins minerals and micronutrients - but obviously not B12 or folate!

🤗🤗🤗

[bookish in reply to Wwwdot]

What a great post, very informative and food for thought! Thank you x

[Treesong2023]

Speaking for my body and its peripheral nerve damage, I can say that my own regime of a month of high B12 and Co-Factors loading worked to stop the pain in my feet within 4 months..i can wear my heeled strappy sandals ( vital test!) my energy came back, better sleeping...feeling of well being began to return too...but i have dips, and still have numbness and tingling sometimes. Dunno why? I was on 1.5mg EOD, then gradually went to every two weeks. That didnt work! My energy fell, brain fuzzy was back and ...my right foot pained me a bit...but my left didnt..? I realised then that my absorption issues persist so, i am staying on my regular dose regime.

Anyways, I am now on 1.5mg every 3 days, plus my co-factors. I go EOD when i do a lot of walking - I am now on 6+ mile walks - having dropped to half milers 18 months ago. Like Www.dot...i try and listen to my body and play the long game. Good Luck!

[JesusMercy60 in reply to Treesong2023]

hello Treesong2023,

thank you for your post, its always helpful to hear others. So I was going to ask if you were deficient for a long time? and did you have a long time of recovery ? I'm in the 5th month of injections. I'm still getting new nerves coming up with reversing out but I am a lot better than before. If I could get my stomach to get better that would help.

[mcg-woo]

Hello! My recovery was absolutely delayed by an inadequate injection schedule. I never had loading doses. When I managed to get weekly injections, they were reduced to every other week once blood work showed levels over 2,000. I didn’t start to get better until I was on long term weekly injections. I recently had a relapse due to the US shortage of hydroxo and have had to increase frequency and dosage levels to try and get back to being symptom-free. Still not quite there yet as it’s taken some trial and error, but I’m definitely making progress. Best of luck to you along your recovery journey.