Does anyone else get ill before their... - Pernicious Anaemi...

Pernicious Anaemia Society

32,679 members24,077 posts

Does anyone else get ill before their next round of B12 treatment?

LittleMikiStark profile image
5 Replies

Hi all,

I have recently been diagnosed with PA, after a very long time of not know "what was wrong with me". My symptoms are mostly the neuro ones, paranoia, hallucinations, depression etc. but I also have always suffered with "a nervous stomach".

It is wild to me how everything I have ever suffered with, which was seemingly unrelated, has been linked to PA.

Anyway, I had my first round of B12 treatment about 3 weeks ago, and I'm due for my next injection next week. But for the last couple of days, I have felt rotten! I've been vomitting, have awful nausea, weakness in my body and feeling really down in the dumps.

Does anyone else find that this happens to them before they are due their next round of B12? Does it get better?

Thanks. Miki.

Written by
LittleMikiStark profile image
LittleMikiStark
To view profiles and participate in discussions please or .
Read more about...
5 Replies
jade_s profile image
jade_s

Sorry you are suffering!

If you have neuro symptoms, they really need to continue with loading doses.

What country are you in? Did you have loading doses , 6 doses every other day for hydroxob12, daily for 1 week if cyano?

Many of us have found that all their weird, seemingly unrelated issues all disappeared with proper B12 treatment.

Nackapan profile image
Nackapan

Vomiting unusual.

I had alot of nausea amongst other Nero symptoms.

As suggested by jade-s you should really be on

Every other day b12injections until no further improvement.

Ask your doctor to read the guidelines

It's early days and a rocky road.

Hope you see improvements soon.

PhilAB profile image
PhilAB

If you have PA then read NICE guidelines and research how long b12 stays active in someone with PA.

Inject at least EOD.

HappyMonk profile image
HappyMonk

I have been self injecting after about a year of daily high dosage B12 sublingual lozenges.I wanted to work up to one injection per month but now seem to have settled on 1-2 wk, depending how I feel.

It seems like docs have settled that 1 shot per month or even 2 months is enough, and often worry about high blood values of B12.

I think most PA patients would probably benefit from a much higher frequency.

If I miss my weekly shot I start getting anxious, short tempered and my cognition declines. If I wait longer my heart starts playing up and I get sleeping problems. Wait even longer and I get severe neurological symptoms.

All of this is prevented by timely shots.

B12life profile image
B12life

2+ years in now and found that despite any amount of meat I eat + was taking 100mg of b12 per day, I just don't absorb. Every time I listened to the docs and spaced out my injections I would have no up back at square one. Learn how to self inject, get your own supplies and inject daily (if cyanocobalomine) or every other day (EOD) if with hydroxocobalamine.

B12 is not toxic unless you have a preexisting liver or kidney function issue caused by something else, only then can b12 be a concern. Which liver and kidney function tests will rule out.

Once kidney and liver functions are ruled out, b12 is not toxic at any frequency or amount. This info is backed by medical journals. however doctors seem to misunderstand this and think it's harmful. This is why many of us self inject (SI). However all the better if you can get a doc to understand, it's just so rare.

Read

ncbi.nlm.nih.gov/pmc/articl...

Great info:

stichtingb12tekort.nl/engli...

And many here from PAS.

pernicious-anaemia-society....

there are no dumb questions so keep asking here on this forum. People are so supportive.

Not what you're looking for?

You may also like...

Oral (passive) treatment of B12

In a recent discussion I noticed an interesting point which I had not picked up. "I am not sure...

I'm new here - does anyone else take sublingual B12 tablets as a treatment for PA?

I had a nasty reaction to B12 injection recently and have opted to take Hydroxocobalamin 1mg per...

Why does the cause of B12 deficiency matter?

On the PAS website, I was surprised to read the following: "Even where low levels of B12 is...

B12 from blood to cells - how does it get there?

Like so many others. I am finding it nearly impossible to get past my GP with regards to B12...
Hypopotamus profile image

anyone else get this?

Hi, Do other people with PA still have occasional bad days even though the regular b12 injections...
sarahjaneR profile image

Moderation team

See all
Foggyme profile image
FoggymeAdministrator
Gambit62 profile image
Gambit62Administrator
taka profile image
takaAdministrator

Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them.

Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked.