Hi, I got diagnosed with PA recently. I am in monthly shots for now after the loading doses. While browsing through, I saw the B12 tablets combined with Folic acid and Intrinsic factor. Has anyone tried these combination and effective for PA on absorption? Are there any side effects if it works? Does it work?
amazon.com/Intrinsic-Factor...
I am in USA and found in Amazon and couple of nutritional websites. Please advice.
No , as you have Pernicious Anaemia, you will not be able to absorb the vitamin B12 in the tablet or just a minuscule amount . You will be able to benefit from the folic acid , but not the Intrinsic Factor . With P.A. You need B12 injections FOR LIFE. . , at a regularity that will keep the symptoms at bay . This varies from patient to patient .
Pernicious Anaemia is an incurable Autoimmune condition , which seldom comes alone . A common “companion “ is a thyroid condition or Rheumatoid Arthritis , but there are over 100 other autoimmune conditions. But with the correct treatment you can live a normal healthy life with no disadvantages . Best wishes .
Interestingly, I cannot find these for sale in the UK (at least not for humans).
If they worked I would expect them to be used instead of injections.
As my PA was diagnosed as I have intrinsic factor antibodies I assume the addition of IF in tablets won’t help as my immune system will cancel it out. That just leaves the B12 in the tablets which I can’t absorb without IF (apart from possibly a minuscule amount by passive absorption).
I'd be a bit wary of the product, just because of the caveats around FDA at the bottom under legal disclaimers, but they are probably the same legal caveats that you would find on any vitamin product.the small number of reviews seem to include a high number of people using it to treat pets.
The details on the manufacturer's website are the usual hype.
It looks like the intrinsic factor content comes from animal products which means that its refined and may well vary quite a bit from tablet to tablet.
I didnt realise you could take intrinsic factor in a tablet?
Yes it is in my Betaine HCL tablets
Is this true, does it compensate for the lack of Intrinsic Factor? If fo what is the best dosage?
No , it is useless . If it worked , PA patients wouldn’t need to have injections .
Yes it is true it is my my HCL betaine pills I take to acidify my stomach. I doubt it helps me absorb B12 any better as I SI EOD anyway.
One way would be to conduct your own tests. Many people on here suggest you need more B12 for all of your symptoms or that only injections will work. You may want to try it. Personally I wouldn't though. It just so happens I noticed the IF was in the tablets - it is not WHY I bought them.
Thank You all. Reading through the advices, it looks like there is no evidence on the IF pills efficiency. I checked with my Gastroenterologist and he suggested to try and see if it works. He does not have any idea on this but he said that B12 alone orally does not work at all. He is saying to keep on with injection and try oral combination and see if it helps.
I have tiredness, lightheadedness, blurred vision (Done Ophthalmologist and Retia specialist consultation and tests and all good on my vision and eye health) and breathlessness sometimes (ECG taken was normal). My PCP, Neurologist and Gastro all saying that monthly injections are standard here in US after loading doses (weekly 1 for 4 weeks) and I do not need more than that. The half life of B12 is high and it will take little time on healing process but I would be ok soon and have patience. So I was trying to keep up with something in-between my monthly injections to get rid of my symptoms or have to try self inject in-between that I am exploring in parallel. I am already taking 5000 MCG Oral tablet daily to see if any passive absorption helps. My PA was diagnosed in Jan so I am not sure if I have to wait for few months to see the improvements.
I'm now totally confused about folate/folic acid/B12 combination.
16 year old b12 135, negative intrinsic factor
on b12 treatment, when start folic acid?
