IM vs SQ

[Sgboyd]

Is there a difference in absorption? Does one last longer than the other? Or is it a matter of dosage (larger doses need larger areas of injection).

[fbirder]

I've not been able to find any experiments that have compared the two. There will be little difference one way or the other.

[Shadowlight]

I have read that hydrocobalamin stays longer than cyancobalamin. I switch to hydro next week. FYI. Cyan worked fine for me. I'm switching only because I have not been getting an adequate supply. I am going to be taking larger dose (2ml instead of 1 ml, because that's what these ampoules hold). I believe that hydro will work fine, and I'll let you know.

[wedgewood in reply to Shadowlight]

2ml indicates the amount of saline used in the ampoule ( millilitres ) , It has nothing to do with strength (amount of B12) .Most ampoules are either 1mg x 1ml or 1mg x 2ml ( same amount of B12 ) except for some Pascoe ampoules which are 1.5 mg x 1 ml .

[Shadowlight in reply to wedgewood]

Ah. did not know. Thank you. I have learned so much on this site. My people!

[Nackapan]

I have both . Initially IM at the surgery only. Since lockdown May 2020 I do sc at home and about 6 weekly get an IM one by a nurse.

The only difference I've found is it seems to get into the system quicker by IM.

L thought im would last longer but for me this doesn't seem to be the case.

I continue to have both as covering all angles. Alm IM was teally hurtingbmy arms.

I dont always get a good response whether IM or sc .

It certainly gets into your system whatever route

It would make sense IM would last longer initially thought this the case . Not convinced though.

Will stick to the regime at present.

It does say on the German Rotexmedica b12 for sc and IM .

[TFH1 in reply to Nackapan]

Just replying to Nackapan comment about IM hurting in arm. I ask nurse to do IM in upper buttock which is much better.

[Nackapan in reply to TFH1]

Mine will not do anywhere but arm. Doesnt always hurt.

Just when every other day for months I got sore.

Last one had ti check shed done it!