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New and needing help with results B12 and Folate

NIC777 profile image
12 Replies

Hi!

I’m hoping someone can help interpreting some recent results. I had bloods done at my GP and also private with Blue Horizon as my GP insists I am fine. My symptoms are extreme fatigue, weight gain, depression, insomnia.

I have added my blue horizon test results which I shared with my GP and they still said I was fine. Any advice?

Thanks xx

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NIC777
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12 Replies
JanD236 profile image
JanD236

Your B12 is in the normal range, albeit at the lower end. However, your folate is below the normal range and so this would be my first thought for your feelings of extreme fatigue.

Folate is generally found in green vegetables (see sources if you google ‘folate containing food’). You could also try a supplement, either a daily multi vitamin containing 400mcg of folate/folic acid or just a 400mcg folate/folic acid supplement.

Extreme fatigue could certainly lead to feelings of depression which can in turn lead to insomnia and maybe poor food choices.

I’m no expert though so maybe others will have a view which may help.

I wish you well and hope you find answers.

SlowDragon profile image
SlowDragon

In your other post on Thyroid site you added

NHS result

B12 177ng/L (145-910)

This is very low

fbirder profile image
fbirder in reply to SlowDragon

No.

177 is within the normal range, not very low.

fbirder profile image
fbirder

Your B12 looks OK, but that doesn't rule out a deficiency (although it's unlikely). Your folate is low and could produce your symptoms.

I would take 50 mcg of B12 a day, plus 400 mcg of folic acid for a month or three amd see what happens.

Cherylclaire profile image
CherylclaireForum Support

Your B12 level now seems okay. Have you been supplementing or been given injections since ? Improving B12 content in diet ?

If your B12 was 177 ng/L at some point as SlowDragon pointed out, (despite being considered within range: 145-910 ng/L) - this was certainly low enough to have given you symptoms.

At 196 ng/L, I could barely stand up straight. Luckily for me, my local range started at 197 ng/L so I was treated. My folate was 5.5 at the time and ferritin in 40s.

I would ask GP - if this original B12 reading was initiated by her/him and on your records - why it was this low previously.

Your folate level is clearly below where it needs to be . Symptoms can include fatigue and gastrointestinal problems, similar to some B12 deficiency symptoms.

Also find it very strange that, if B12 is over 569 ng/L, the advice given is to "consider reducing dose" when the top of the range here is 910 ng/L ! Why the overconcern at top end ?

NIC777 profile image
NIC777 in reply to Cherylclaire

Hi:)

I think the type of measurement is different between the NHS and Blue Horizon test.

NHS 177 (145-910)ngl

BH 315 pmol ?

I have not supplemented or changed anything. My symptoms actually seem worst if anything

Xx

JanD236 profile image
JanD236 in reply to NIC777

Different units of measurement and different labs testing using different machines. Shows the importance of stating the normal range provided by the lab as a straight comparison of the results would be meaningless.

Cherylclaire profile image
CherylclaireForum Support in reply to NIC777

1 pmol/L is equal to 1.355 ng/L, which makes the difference between the two results, using a like unit of measurement, even wider than it appeared.

The Blue Horizon level of 315 pmol/L seems to be a healthy one.

Either unit of measurement can be used for serum B12 test results.

I do not know whether I'm right in assuming that the lower level (NHS) came first, and what time elapsed between that and the second test.

The symptoms you have described could be due to one (or more) of a few conditions. One thing is clear - folate could be improved. This has been highlighted on your results. Even if your GP does not want to prescribe for this, it is quite important that supplementing is monitored to ensure that it is sufficient and effective in raising your folate level, and that you do not raise it too high by over-supplementing.

It took me a couple of years to get my folate to a healthy level and be able to maintain it.

I now just take a daily general multivitamin and mineral tablet.

Greenhedging profile image
Greenhedging

This may seem leftfield, but have you been assessed for a sleep disorder? I had similar symptoms plus B12, folate and D3 deficiency, but also had untreated sleep apnea. I had to push quite hard to get sleep test (done at home), was still left untreated for years. Now have a CPAP machine and feel much different. Frequent trips to the loo at night is also a sign. If you snore try recording this on your phone. Just a thought.

NIC777 profile image
NIC777 in reply to Greenhedging

No I hadn’t thought of that to be honest. I have awful problems sleeping but assumed it was due to my other symptoms. X

Tiggers321 profile image
Tiggers321

Looks like your b12 is borderline 200-300 is considered ok ish and low folate you could increase you b12 intake within you diet my adding in ...

Fish

Red meat

Liver

Clams

Milk

Cheese

Eggs

I am sure your doctor would have suggested this is he felt the results warranted it I hope you find some relief from your symptoms. But go back if you feel unsatisfied with your results we know our own bodies and should trust instincts

NIC777 profile image
NIC777 in reply to Tiggers321

Thank you for your support and comments x

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