Many of you know that a few of my symptoms started returning about 5-6 weeks into injection treatment. I saw my Neuro today and I asked why I can’t change my injections back to weekly instead of monthly (I had 7 loading doses plus weekly for 4 weeks) and she had a very good response that made sense. She said that my levels will likely show sufficient b12 from being on weekly injections (fair statement) and that the reason I am feeling some symptoms return is that because nerves were affected during the deficiency and that you can have relapses of symptoms for some time (Seth12345 has said about the “roller coaster” with symptoms coming and going and others said it’s like “waking up” the nerves) and she said there’s no reason to inject when levels are normal or likely above normal (same with MMA - they should be lower with injections) because there’s no reason to do so, and that what I’m feeling is “flare up” pain because my body has produced these pains (neuropathy) before and the nerves are still very sensitive and can “fire” here and there. I told her about this forum and how people say that their symptoms get better with self injecting more often than the regular schedule and she said that symptoms can come and go and get worse or better all while healing but she kept referring to if you have normal levels FROM the injections, she can’t advise overloading because it would add no benefit.
I also have a script called gabapentin (pain medication for nerve pain)that she gave me back when I was first diagnosed and she said to take that as needed to manage the pain (My pain isn’t really that bad so I won’t) and that the reason they prescribe this is to get you through the bouts and flare ups that can come and go. She did offer to test my b12 and MMA right before the next dose, which is monthly, (so I’ll be 4 weeks from the last injection) and that if I am low, she would then prescribe a different regimen.
What she said really made sense but I know a lot of you feel that self injecting is helping. And if so, that is great. But I have trusted this Neuro for a while now and her medical reasoning sounds good to me, plus I have a remedy if the pain does get worse from the flare ups, but I just wanted to share this as informational.