Does anybody get manic after injections? - Pernicious Anaemi...

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Does anybody get manic after injections?

ProfessorMcGonagall profile image

I’ve found that after injections I can be a bit manic/impulsive - it feels as though I suddenly have lots of energy and I make unrealistic plans for the future (as though I’ll always have that much energy!).

Wondered if anybody else finds this?

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ProfessorMcGonagall profile image
ProfessorMcGonagall
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5 Replies
Gambit62 profile image
Gambit62Administrator

I can't say that I do but B12 is used in the COMT process that recycles neurotransmitters (as a methyl donor) and it seems to be a process that is problematic if it runs too fast or two slow so possibly something is going on that temporarily makes the process go into overdrive for you.

LowB12 profile image
LowB12

I don’t feel manic but do feel like I used to years ago...much more energy, clarity of thought, more productive. I guess if I hoped I would be like that full time I would make unrealistic plans & set myself up for a fall.

I definitely have a better week post injection

pvanderaa profile image
pvanderaa

That is part of the roller coaster ride. I find that the more severe the symptom is after the injection, the lower my B12 was before the injection. Means you probably need more B12 to fill in between jabs.

Are you supplementing with folic acid and a daily multivitamin? Also try Methylcobalamin sublinguals daily.

Do you keep a logbook and assess the severity of each symptom?

Psychological symptoms like this are the result of repair of neurological damage if they appear after the jab. These symptoms are very counterintuitive and can confuse the issue of treatment levels.

Cherylclaire profile image
CherylclaireForum Support

I know what you mean about unrealistic and overenthusiastic planning !

I also get slightly anxious about the time-frame: rushing to do too much before it all goes pear-shaped again which is of course a self-fulfilling prophecy. Makes me impatient to get things done - with often disappointing results. It does, though, make me hopeful that longer-term improvement is still a possibility.

It doesn't always happen. Sometimes, nothing changes -it feels like maybe I've just injected Ribena. It is then a long air-hungry struggle waiting for the next injection. Why I'm waiting on these occasions, I'm not entirely sure.

I wish instead of 1 injection every other day, I could have 1/2 every day. I might then feel more "normal".

PaintLadie profile image
PaintLadie

No, but I wish I did. I would unleash myself on the dishes and organizing everything!

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