IF high values

[Gumball77]

Hi. I have been diagnosed with pernicious anaemia in February 2018. I receive injection every 3 months, although i feel i need them monthly.

Just tested my Intrinsic Factor and the results are 38.5 , and normal is <6

can't seem to find anything online about what these results, so if anyone knows anything, i will be so grateful.

Many thanks, Alina

[Sleepybunny]

Hi,

Are you in UK? I'm asking because B12 treatment varies between countries.

Recommended UK B12 treatment for b12 deficiency without neuro symptoms is ....

6 B12 loading jabs over 2 weeks followed by a jab every 2 or 3 months.

Recommended UK B12 treatment for b12 deficiency WITH neuro symptoms is .....

A B12 loading jab every other day for as long as symptoms continue to get better (could mean weeks even months) then a jab every 2 months.

UK B12 documents

BSH Cobalamin and Folate Guidelines

b-s-h.org.uk/guidelines/gui...

Flowchart from BSH Cobalamin and Folate Guidelines

stichtingb12tekort.nl/weten...

BMJ B12 article

bmj.com/content/349/bmj.g5226

BNF

bnf.nice.org.uk/drug/hydrox...

NICE CKS

cks.nice.org.uk/anaemia-b12...

B12 books I found useful

"What You Need to Know About Pernicious Anaemia and B12 Deficiency" by Martyn Hooper

Martyn Hooper is the chair of PAS (Pernicious Anaemia Society). Book is up to date with UK b12 guidelines.

"Living with Pernicious Anaemia and Vitamin B12 Deficiency" by Martyn Hooper

Has several case studies.

"Could it Be B12?: An Epidemic of Misdiagnoses" by Sally Pacholok and JJ. Stuart (USA authors)

Very comprehensive with lots of case studies.

PAS (Pernicious Anaemia Society)

Based in Wales, UK.

pernicious-anaemia-society....

PAS tel no [phone] answerphone

PAS support groups in UK

pernicious-anaemia-society....

B12 Deficiency Info website

b12deficiency.info/

UK B12 Blogs

Martyn Hooper's blog about PA

martynhooper.com/

B12 Deficiency Info blog

b12deficiency.info/blog/

I am not medically trained.

[Gumball77 in reply to Sleepybunny]

Hi.

I am in the UK.

Thank you so much for the repky.

I will go through them

[fbirder]

Your high IF means that you definitely have PA. Treatment will not affect that.

[Frank77 in reply to fbirder]

I was wondering if a very low IFA figure means that PA can be ruled out? I have seen many times on this site that the IFA test is unreliable and often gives false negative results. But does a low figure mean that it is more likely to be a real negative, so to speak? My IFA result was 2 [0-7 normal; 7-10 equivocal; greater than 10 positive].

[fbirder in reply to Frank77]

No, a low IFA test doesn’t mean anything. It cannot be used to rule out PA. Otherwise the chair of the PAS wouldn’t have it.

[Frank77 in reply to fbirder]

I see. Thank you.