Folate: Hi my B12 is 320 been on... - Pernicious Anaemi...

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Folate

lilly60 profile image
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Hi my B12 is 320 been on injections for 6 years now

My results last time were 400

To me obviously I am not maintaining it at all

Not according to my GP it's not a problem

So still on 12 weekly

Do you think it would do any harm to take folate and if so how much

I am so tired yesterday I couldn't function at all

Thank you all

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lilly60
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clivealive profile image
clivealiveForum Support

It is also important that your Folate level is monitored as this is essential to process the B12.

There is a complex interaction between folic acid, vitamin B12 and iron. A deficiency of one may be "masked" by excess of another so the three must always be in balance.

Symptoms of a folate deficiency can include:

symptoms related to anaemia

reduced sense of taste

diarrhoea

numbness and tingling in the feet and hands

muscle weakness

depression

Folic acid works closely with vitamin B12 in making red blood cells and helps iron function properly in the body.

It would pay you to have your Folate level checked but personally I have taken 1 – Folic Acid 400μg tablet every day for more years than I can remember in addition to what can be found fortified into many breakfast cereals etc.

Do you have an absorption problem causing your B12 deficiency?

I'm not a medically trained person but have had P.A. for 46 years and get cyanocobamalin B12 injections every three weeks.

lilly60 profile image
lilly60 in reply to clivealive

Thank you had bloods done the only one the doctor commented on was I was short on iron just to introduce more in my diet

lilly60 profile image
lilly60 in reply to lilly60

Also my pv is running high 2.20

But they just give out these figures and no action taken

But had problems with pv for numerous years

Also my information markers are always between 13 and 22

I see a Rheumatoid Specialist for this

lilly60 profile image
lilly60

Thank you x

Gambit62 profile image
Gambit62Administrator

after loading doses it is not the serum B12 level that should determine your treatment it is your symptoms.

B12 levels in your blood will be astronomic after your shot and then reduce over time as small amounts are used, but mainly becasue excess is removed by your kidneys, or lost because your body tries to store it in the liver but as it is released through the ileum most if it then passes through the gut rather than being reabsorbed in the ileum.

The rate at which you lose B12 is greater when the levels of greater

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