long term side effects of b12?

[pslmt]

Hi I'm wondering If anyone has knowledge of research that has been done for side effects of long-term injecting of B12?

[clivealive Forum Support]

I've been having B12 injections for P.A. for more than 45 years and I'm still "clivealive" and over 75

[pslmt in reply to clivealive]

Yes I have been watching. Good job! just wondering about long term use vs the body and other reports thanks!

[Gambit62 Administrator]

People have been using injectable B12 for years - and clivealive is a case in point.

I don't know if there have been any formal long term studies - just that there doesn't seem to be much reported on any problems from long term use.

Do you have a particular reason for asking?

[pslmt in reply to Gambit62]

Thank you for your imput! I see clivealive has been doing it for 45 years! yah! just wondering about long term use vs. impact on body thank you.

[Gambit62 Administrator in reply to pslmt]

tried searching the NCBI library for any studies on long-term safety but haven't managed to get the search worded properly .... or else there really isn't anything there either.

There are studies that came out of scandinavia that show higher rates of cancer and development of larger tumours in patients being treated for B12 deficiency - but that is only a correlation rather than establishing causal mechanisms - which may well be around the fact that being B12 deficient increases your risk of developing a cancer ... and B12 will also promote the growth of cancerous cells as well as healthy cells leading to larger tumours ... but I don't think the study was a long term study .... certainly not on the scale of clivealive 's personal experiment

[clivealive Forum Support in reply to Gambit62]

Love the word "experiment" Gambit62 - I guess it must be working.

I'm certainly not going to stop until I die....

[pslmt in reply to Gambit62]

I find it Interesting why there aren't studies done for this. Thank you for looking into it!

[Gambit62 Administrator in reply to pslmt]

doing any long term studies is really difficult as you need to be able to keep going back to and assessing the same group of individuals - this is part of what initiatives like the UK biobank are doing but it is going to take a long time for the body of information that they are building up to accumulate.

[pslmt in reply to Gambit62]

I would assume it has something to do with where the money for such research is allocated? I wish that PA where more of a topic these researchers would find interesting enough to pursue. (and funded)

[Gambit62 Administrator in reply to pslmt]

it really isn't just to do with money. Long terms studies are really difficult - people are unwilling to commit and even those that do tend to have a very high drop out rate - which potentially leaves you with a very small sample group - too small to make any real conclusions from

[clivealive Forum Support in reply to pslmt]

Are you thinking along the lines of "recreational use" to "boost" performance?

Mine is a case of "needs must" else I would have been dead for over forty years without the B12 injections

[pslmt in reply to clivealive]

Not recreational, I have PA and I must have it.

[pslmt in reply to Gambit62]

I will be a "lifer" on B12 because of my PA, I am curious.

[Gambit62 Administrator in reply to pslmt]

one form of B12 - hydroxocobalamin - is used to treat cyanide poisoning at much higher doses - 5-10,000 times a loading or maintenance shots - as it is low risk - not a long term thing but it's basically safe, providing you manage to get the amounts that you actually need

[Lucy12345]

30 years on b12 hydroxo and no long term effects for me. I think the benefits of having injections would far outweigh the long term issues if there were any. I'd be dead by now without them. There has been a bazillion researches done on the benefits, and the fact that it's so hard to find the few that may indicate otherwise seems to reinforce that it's pretty safe.

[SusanLMckinney]

I've been injecting for 17 years, only side effect is health for me. My B12 was undetectable when someone finally tested it