Hello, I posted 4 days ago after experiencing breathing difficulties after my 3rd loading dose. Thanks to everyone's support I had the courage to have my 4th loading dose yesterday and am due my 5th tomorrow. I have never suffered with anxiety but today my anxiety has increased and so I am feeling worse than I've ever done (my diagnosis came after I experienced shaking and memory issues but I was ok in myself ie no anxiety). I have read that if your B12 levels are low, you are more likely to react/show symptoms when having the loading doses. My reading was 152 so just wanted to hear others experiences. Is 152 particularly low? I've noticed also that if I don't eat regularly the anxiety gets worse - I used to be able to go all day without food (not good I know). The support of this forum has got me this far and I'm really hoping that I start feeling better soon and that doses 5 and 6 are positive experiences ie no more side effects.