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what is the difference

Lucieb01 profile image
3 Replies

could someone plz tell me the difference between vitd&vitd3

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Lucieb01 profile image
Lucieb01
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jade_s profile image
jade_s

There are two types of vit D supplements you can take: D2, and D3. The D3 form is what most people recommend for supplementing. When people say "Vit D", they're usually referring to the D3 form.

mayoclinic.org/drugs-supple...

As for the blood test, there are also 2 tests: 1,25(OH)₂D test, and the 25(OH)D test. The 2nd one is preferred, though the 1st one can be useful in certain scenarios.

Gambit62 profile image
Gambit62Administrator

from this acticle - sounds as if they are slightly different chemically and the main difference is the way they are manufactured. As with other dietary vitD, and that obtained from sun exposure they are intert forms that require more processing by the liver and kidneys before they can be used by cells.

ods.od.nih.gov/factsheets/V...

In supplements and fortified foods, vitamin D is available in two forms, D2 (ergocalciferol) and D3 (cholecalciferol) that differ chemically only in their side-chain structure. Vitamin D2 is manufactured by the UV irradiation of ergosterol in yeast, and vitamin D3 is manufactured by the irradiation of 7-dehydrocholesterol from lanolin and the chemical conversion of cholesterol [6]. The two forms have traditionally been regarded as equivalent based on their ability to cure rickets and, indeed, most steps involved in the metabolism and actions of vitamin D2 and vitamin D3 are identical. Both forms (as well as vitamin D in foods and from cutaneous synthesis) effectively raise serum 25(OH)D levels [2]. Firm conclusions about any different effects of these two forms of vitamin D cannot be drawn. However, it appears that at nutritional doses vitamins D2 and D3 are equivalent, but at high doses vitamin D2 is less potent.

Evolved2 profile image
Evolved2

Vitamin D2 is an inactive form of vitamin D, and found in some plant forms like mushrooms. Absorption is not good.

D3 is an active form of Vitamin D found in animals and humans. Vitamin D3 is far superior for the human body. Vitamin D3 is created ( actually it is not a vitamin but a hormone) when sun hits the skin and cholesterol is converted to vitamin D3.

I hope that helps :)

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