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Newbie Loading injections

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Does anyone know if this is correct

After loading injections should bloods been done 10 to 14 day after

.Then bloods eight weeks later

My level was 173 when diagnosed. GP, said will need them 3 monthly for life, I've got graves disease and under active thyroid.

Thanks

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11 Replies
clivealive profile image
clivealiveForum Support

Hi Hidden if you are referring to the serum B12 test there is absolutely no point in testing once injections have started but as I'm not medically qualified I don't know about testing for your other symptoms.

However it would be worth asking for your Folate level to be checked as this is essential to process the B12. Do you know what it was before you started the injections?

Secondchance profile image
Secondchance

Please see abijah post below

Guidelines recommend no point checking bloods after treatment started (for B12).

If you have neurological symptoms the treatment is different so check that out.

Most people take a folic acid or methylfolate supplement to ensure they make best use of B12. I also take B complex

in reply toSecondchance

Thank for your replies clivealive and secondchance .Can't take folic acid. Have had folate tested OK, but still waiting for copies of all bloods, have written twice to GP requesting this.

Ps have graves disease and under active thyroid

fbirder profile image
fbirder

My summary document contains links to several expert papers and summaries of key points from those papers. One of those summaries explains how, once supplements have started, further testing is unnecessary.

frankhollis.com/temp/Summar...

in reply tofbirder

If I haven't already said thank you for your help

Gambit62 profile image
Gambit62Administrator

The blood tests might be useful in monitoring how well your body retains levels of B12 in your blood and if they show a sharp drop would indicate that you needed B12 more frequently (kidneys efficient at removing it), so low results and a significant downward drop is useful evidence that you need shots more frequently. However there is so much more to B12 deficiency than the levels in your blood that high levels after shots aren't going to tell your GP much if anything as they don't say anything about what is actually happening with transferring the B12 from your blood to the cells where it is really needed and there are a number of things that can interfere - some of which may actually start as a result of having had your levels raised very high by receiving a B12 injection. It is the symptoms that will really count.

10-14 days does sound a bit like a waste of time. 8 weeks might be useful if it shows that levels have dropped again but also likely to be a waste of time. NICE guidelines aren't very clear - talk about not testing unless there is reason to suspect non-compliance with treatment and if you are having treatment by a nurse and it is on your records then they know that there isn't non-compliance.

Testing because symptoms have recurred and finding low levels would only rule out one reason for the symptoms returning. It wouldn't rule out a functional deficiency because something is interfering with transfer/use at cell level. Treatment in both cases would be same - more frequent shots - so testing seems rather pointless. Would only be useful if needed to monitor something other than B12 because suspected there might be more than one thing going on.

fbirder profile image
fbirder in reply toGambit62

I thought the NICE guidelines said that further testing is unnecessary unless folate compliance was questioned. I guess they think that it would be hard not to have your B12 injections without the medics knowing about it.

Gambit62 profile image
Gambit62Administrator in reply tofbirder

A While since I looked at the guidelines and the intention may be in relation to oral treatment for a dietary deficiency but don't think it was purely in relation to folate.

in reply toGambit62

Thank you for your help

in reply tofbirder

Looking into where I can get b12 shots from that is reliable

Thank you for your help

in reply toGambit62

Thank you for that, with the Gp I've got I will see if I can order b12 shots.

I have to diabetics at home so I will know what am doing.

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