My GP says that with a B12 test result of 444 I'm absolutely not suffering from B12 deficiency. But I have been on 25mg folic acid per week to help with the side effects of an RA immune supressant drug, Methotrexate. Over the past 4 weeks I have been getting severe peripheral neuropathy (pins and needles everywhere and numbness in my legs and feet). I decided to stop taking Methotrexate and now I've been told by my doctors that I wouldn't be allowed it again in case it has damaged, or would cause eventual damage to my peripheral nervous system.
I don't want to come off this drug permanently and risk my RA returning, only to find there was another cause and it's just gone undetected. I asked my GP about the possibility of folic acid compromising the B12 results but he knew nothing about this. The rheumatologist just said that it wouldn't neutralise such a healthy B12 result.
They are probably both right but I just wondered if anyone can tell me how much a large dose of folic acid could skew my B12 results and whether, if the neuropathy continues, it would be worth my while taking supplements anyway.