Parkinson's Movement
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Seroquel question

Hi all. I'm new here. This is my first post.

I was diagnosed with Parkinson's over a year ago and am not on any medication. A few months ago I started having visual hallucinations. My doctor prescribed Seroquel.

I can't quite follow the logic. Maybe I've got it all wrong, but if Seroquel is a dopamine antagonist, is it not counter intuitive to take it when I am not on any dopamine replacement therapy? Surely I need all the dopamine that's available to me.

What do you think? Have I got that all wrong?

6 Replies

I would get another opinion if it were me. My spouse, now deceased, took seraquill ( getting it from the street) and became someone I couldn't feel safe around. His behavior became erratic and I had to tell him to get out. This drug causes hallucinations.

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That's what is confusing me. I'm being prescribed Seroquel precisely for hallucinations!


You have got it exactly right. You should run, not walk away from this physician and find someone who knows what s/he is doing. This page has got a good flow chart for how to treat PD hallucinations

Pimavanserin is an anti-psychotic specifically for PD hallucinations and does not interfere with dopamine.


There is only one type of medication I know of that helps you to retain the dopamine you already have in your brain. Dopamine normally gets destroyed if it has not been used within a short period of time That is a different type of medication and it is called an MAO-b Inhibitor. There are 2 types on the market, Eldepryl (Selegiline) and Azilect (Rasagiline) .

I was initially put onto sinemet & symmetrel for 2 years in 1992 and then taken off those in 1994 and put onto Eldepryl. 8 years later, I was able to come off the eldepryl and have not needed to take any Pd mediation since 2002.

When I was put onto the Eldepryl I also started to do Fast walking and that, together with stress management, Positive attitude, brain exercises, eating properly and learning how to use my conscious brain to control my movements, has turned my life around.

Look at my profile or visit my website, and learn ore about it. There are over 400 articles about how to deal with your Pd and they don't cost a cent.


Thanks everybody.

I'm only just realizing how complex this all is. My doctor is talking about getting me on to Azilect. I need to speak to him about this.

I'm in Australia and as far as I know Pimavanserin is not yet available here.

John, I will certainly have a look at your website. I was very interested to read about your struggles in Norman Doidge's book (if I recall).



Whenever you are seen by an MD and you don't like his Dx &/or Tx get a second or third opinion; NEVER be your own doctor.


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