immune modulation in PD : Scientists achieve research milestone

Scientists achieve research milestone with Parkinson's disease

Date: March 27, 2017

Source: University of Nebraska Medical Center (UNMC)

Summary: In a Phase I clinical study, researchers were able to transform

the immune system by taking cells damaged in Parkinson’s disease and

making them cells that protect and defend against brain injury.

sciencedaily.com/releases/2...

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open access

Evaluation of the safety and immunomodulatory effects of sargramostim in

a randomized, double-blind phase 1 clinical Parkinson’s disease trial

nature.com/articles/s41531-...

3 Replies

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  • Sounds promising - like so many of these trials...

    Still waiting

  • So this is a repurposed drug originally used to increase t-cells. In that case off it works can't they apply for that special status to move things along?

  • Perhaps Dr. Gendelman (lead author) would appreciate a note of appreciation and encouragement.

    Howard E. Gendelman

    Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, NE, USA

    Contact Howard E. Gendelman

    nature.com/articles/s41531-...

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