Over the last couple of weeks my meds have been taking forever to kick in and then have gone off early. I take Stalevo, Requip and half Sinemet for Parkinsons and other meds for different problems. I am beginning to wonder if these meds are working against each other. Is this possible? Last weekend I had a series of steroid injections for facet joint pain and my meds are all over the place. I was wondering whether anyone else had experienced anything similar or whether I am going through a bad patch.