Yea I know, I am on hiatus, but I am rendering video files which take about 2 hours to make 1 and I was bored (blah, blah, blah....). Threads on Nilotinib has been posted often on this site (dating back 3 years) and I decided to investigate it a bit. When you read this thread you will understand why I posted this important information.
CPT Collaborates to Assess the Clinical Use of Nilotinib in Parkinson's
Nilotinib (formerly AMN107), a highly selective BCR-ABL tyrosine kinase inhibitor, is effective in patients with Philadelphia chromosome-positive chronic myelogenous leukemia in chronic phase following imatinib resistance and intolerance.
Antileukemia effects of xanthohumol in Bcr/Abl-transformed cells involve nuclear factor-κB and p53 modulation
"We show that xanthohumol strongly inhibited Bcr-Abl expression at both mRNA and protein levels and show that xanthohumol caused elevation of intracellular reactive oxygen species and that the antioxidant N-acetylcysteine blunted xanthohumol-induced events."
"As structural mutations and/or gene amplification in Bcr-Abl can circumvent an otherwise potent anticancer drug such as imatinib, targeting Bcr-Abl expression as well as its kinase activity could be a novel additional therapeutic approach for the treatment of Bcr-Abl(+) myeloid leukemia."
Raising intracellular reactive oxygen species in cancer cells is an attempt to kill them. NAC blunted this effect.
With investigation, I found that NAC is not good to take if you have cancer:
N-acetyl-cysteine (NAC): good for some things but dangerous with cancer.
So if you have any form of cancer, do not take NAC.
What is xanthohumol?
"Xanthohumol (Xn) is a Bioactive Flavanoid Antioxidant molecule found in the flowering Hops Plant. It is 200 times more powerful than Resveratrol, the world renowned Antioxidant found naturally in Red Wine."
Beer compound could help fend off Alzheimer's and Parkinson's diseases
"In lab tests, the researchers found that the compound could protect neuronal cells and potentially help slow the development of brain disorders. The scientists conclude xanthohumol could be a good candidate for fighting such conditions."
Can you purchase xanthohumol?
The file is completed.