Nilotinib in Cognitively Impaired Parkinson Disease Patients 001 Clinical Trial Accepting Now

[p-oui]

foxtrialfinder.michaeljfox....

Open Label Dose Escalation of Nilotinib in Cognitively Impaired Parkinson Disease Patients With Elevated Cerebrospinal Fluid and Blood α-Synuclein

Contact:

MedStar Georgetown University Hospital, Washington, DC

Connell Owings

[e-mail]

202-444-2658

[jeffreyn]

p-oui,

I've had a look at the webpage you linked to. It says that the status of this trial is "completed".

Jeff

[Isthistheone in reply to jeffreyn]

Gotta be the one DRs Moussa and Pagan completed and reported on in 2015. That was open label, no placebo. Too bad Georgetown and MJFF are feuding. Nilotinib, brand name Tasigna manufactured by Novartis, demonstrated very positive results. Extremely unfortunate that PWP have to suffer for 5+ years for FDA approval. As most are aware, Tasigna is already FDA approved for a specific type of leukemia. Any licensed physician can therefore legally prescribe it "off label" for PD.

In my opinion, bureaucratic red tape, the pharmaceutical industry, and parts of the medical establishment are keeping Tasigna away from sufferers of PD. Tasigna costs for leukemia patients are $13,000 per month. Nothing more needs to be said.

[p-oui in reply to Isthistheone]

It is more than sad, it is a travesty and the cost is lives - I don't know how else to say it. It seems we could speed from 5 years to 1 since it is FDA approved at least but I know that's not possible.

[Hikoi]

A double-blind, placebo-controlled clinical study of Nilotinib (Tasigna®) in patients with Parkinson's disease

adisinsight.springer.com/tr...

[p-oui in reply to Hikoi]

Hikoi thank you! This is great news!

[Isthistheone in reply to Hikoi]

This is very good news. Nothing yet on the calendar at AMC in Albany NY. I hope this has wings and flies really soon. Read up, this drug has more than just promise. Data shows it works!

[CPT_Helen Partner]

This trial is also not recruiting yet.

Many thanks

Helen

[p-oui in reply to CPT_Helen]

Yes it is coming in a few months which is very good news

[rhenry45]

I have 100 grams of the powder form of nilotnib but I am scared to take it due to potential side effects.

[p-oui]

Henry, I don't blame you. I would want to do this under a doctors supervision.

[Mamapaula]

Please take me 79 no health problems I can bring camper and live there for trial. I'm in sc and go to MUSC muffin program. I'm not giving up. Please help our family. The Tasigna is $40 a pill from Canada. [e-mail]

[Scorpgirl]

Georgetown University is actively enrolling patients in the phase 2 trial of nilotinib right now! Great news for the PD community!!!!

[munchybunch]

can you buy Tasigna in Canada ?