"What we have here is a case where the molecular target has been shown to be important to Parkinson's in human genetic studies," says Shokat. "And now we have a drug that specifically acts on this target and reverses the cellular causes of the disease."
The active ingredient in an over-the-counter skin cream might do more than prevent wrinkles. Scientists have discovered that the drug, called kinetin, also slows or stops the effects of Parkinson's disease on brain cells.
if successful in that group the drug could later be tested in a wider array of Parkinson's patients
Kinetin, a cytokinin and plant hormone, is a cell division factor found in plant parts and yeast. Kinetin has also been detected in freshly extracted DNA from human cells.
History
Plant hormones, or cytokinins, were named for their ability to stimulate cell division (cytokinesis). The first known cytokinin was a component of coconut milk. This was used as a standard additive to plant tissue cultures in the lab because of its ability to make plant cells divide. Cytokinins were eventually isolated from coconut milk, immature organs of corn, and various other sources. Studies dating back to the mid-1950s describe the structure and synthesis of kinetin specifically.
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