The differences between serous papillary and clear cell?

Hiah, I had serous pappillary on my ovary and had carbo and taxol - I recently found out I also had clear cell in my uterus but no one else has actually spoken about this to me. When I asked why? - I was told that Serous and clear cell are very similar but I understand that clear cell doesn`t respond well to chemo, unyet my oncologist told me that serous responds really well to the treatment. I question how can they be similar if that is the case? Sorry I can`t be of any help, I am actually really confussed about it now too.

9 Replies

  • I have serous papillary and didnt respond to taxol carboplatin. I need to do a bit more research but kind of a bit scared to google.....

    K x

  • "I have serous papillary and didnt respond to taxol carboplatin".


    Please can you remind me which chemo they are trying next with you?

    I tried caeylx which didn't work either. I am now at a crossroads again.

    Love Lizzie


  • Hi

    Im waiting for a referral to the Royal Marsden any day so I dont know what they are going to give me next. My OC is grade 1 but stage 3 as it had spread to omentum and 5 weeks ago I had debulking that went really well all the tumours were removed apart from a 'film' of cancer on or near the diaphragm. I just cant figure out how it had spread so much if its grade 1 (Ive got the pathology report and seen that for myself) and the onc confirmed that it was grade 1 throughout. I had no symptoms and Im still 'well'- I felt the lump in my abdo thats why i went to the drs. Does anyone know of chemo that is effective for slow growing cancer?

    K x

  • Blimmy that sounds terrifying for you both, May I ask what GRADE your cancers are?

    My serous was an aggresive high grade, but was told that it is more responsive to the carbo, taxol and my CA125 fell by 1,000.

    I am also still confussed by the way I was STAGED at 2c - because it had spread to my bowel and uterus (with clear cell), they also removed my appendix and omentrum but only found cells in those areas. I thought that once cancer had spread it would be staged at a 3 or 4?????? Anyone know.

  • Hi Tina,

    Mine is agressive high grade cancer, so yes it is leaping along and does not respond to chemo (refractory disease). I am currently having the histology double checked at UCL to make sure it is serous papillary. Glad your CA125 is falling. Terrified is not how I feel, I have been upset but all life ends. I know I may not live much longer - I have survived 10 months past diagnosis, but will keep looking for something to prolong life for as long as I can.

    From cancer research Staging:-

    Stage 3 cancer of the ovary means the cancer has spread outside the area surrounded by your hip bones (the pelvis) into the abdominal cavity. Your cancer is also stage 3 if cancer is found in the lymph nodes in your upper abdomen (tummy), groin or behind the womb.

    My knowledge of anatomy can help you no further!

    Love Lizzie


  • Hi Lizzie,

    Reading someone who is going through the same illness makes it a bit better in the sense that you feel your not alone, I was diagnosed with metastatic adenocarcinoma of the ovaries. Meaning I have ovarian cancer stage 3c . last September , I had 4 sessions of chemotherapy (Carboplatin & Taxol) already. And 4 days before Christmas I had a total hysterectomy and omentectomy ( removal of my omentum) I find my chemo was a doddle compared to my operation. I'm now 4 weeks post op and still feels very bloated and uncomfortable. So I would like to hear from others who had the same operations as me. I've seen my consultant oncologist this morning and she told me I'm ready to resume my chemo treatment in 2 weeks time. I needed 6 sessions all together and I already had 4. They had found 3 nodules in my peritoneal lining so I will be given avastin as well for 18 sessions to slow the growth of cancer cells. I have the aggressive form as well. They say have a positive attitude helps a lot.. I have strong faith and prays a lot as well. I also have my moments and cry myself to sleep..

    I hope my experience helps you a little bit, feel free to message me if you have any questions.

    Huggs xxx


  • You sound so brave Lizzie! It`s a miricle how we respond and cope with bad news when we need too, sure we are all dieing, something no man can ever escape from that fact, even when we are healthy, life is passing us by and that`s the way I see things now.

    How old are you Lizzie? I ask because I am interested on the different ages this cancer strikes us ladies. I am 53, was diagnosed at 51, lost my own mother at the age of 47 to the disease( she passed away on her birthday).

    I have inherrited the faulty braca one gene and so has my youngest daughter, still waiting for my eldest daughters results. But hay ho, only 10% of the worlds population have cancer through a faulty inherrited gene, so even without the faulty gene all the human race is at risk. I try to see my glass as half full - we can always swing a situation round to a positive one.

    I am not scared of death - but I am scared of the suffering leading up to it, I just hope that when my time comes it`ll be quick and painless with time to prepare.

    Love from Tina xxxxx with one massive gentle hug !!!!!!

  • Hi Tina,

    I am 45 now. I was diagnosed at 44. Hoping to make it to 46 in late June. I am not brave, I cry sometimes and feel sorry for myself. I try not to make it too often for my own sake and those around me! I completely agree about the dying process being the fear. I have told my husband just to beg them to drug me up. I am sure dying of oc is not going to be easy, but then is birth or death ever easy?

    Massive gently hug gratefully received and returned.

    Love Lizzie


  • Hi, I was diagnosed stage 1a with possibly no further treatment!! After I had my hysterectomy I was told I was stage 2a Grade 3 papillary serous/ Although I had womb cancer,because it had spread into one fallopian tube it is classed the same as ovarian cancer. I had 4 sessions of carbo/taxol & 4days 6-8mins each day of Brachytherapy which I completed at the beginning of April 2016. I am on this watch & wait,not really sure what to say about this. My consultant does an internal examination at each 3month interval,but I still find this worrying as before I was diagnosed originally I had no symptoms until about 3weeks before I had the hysteroscopy following a small bleed. I am post menopausal & will be 72 next week. So far I feel fine but there is always this nagging suspicion that something maybe going on inside that I don't know about.

    I feel very well now, plenty of energy etc. but that does not mean to say that everything is ok, but I am learning to live with these thoughts.


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