New Studies Show Daily Aspirin Use Improves Survival after Diagnosis

[WorriedHusband]

Yet again new studies prove Asprin improves the survival outcomes of patients with ovarian cancer.

moffitt.org/newsroom/press-...

[Lily-Anne]

This comes up a lot. Trouble is there’s a lot of us who can’t tolerate aspirin and it can’t be taken with some treatments

Good news for those who can take it though. A bit like metformin

LA

[Hidden]

I was already taking low dose Asprin for another medical condition for 6 years before being diagnosed with OC.

[WorriedHusband in reply to Hidden]

The studies show that daily use of aspirin may reduce ovarian cancer risk by only 10 percent but provide as much as a 30 percent improvement in survival of women diagnosed and treated for ovarian cancer.

Life time risk of getting ovarian cancer for a woman is 1,5% therefore by use of asprin the life time risk goes down to 1.35% (10% reduction). Very marginal improvement.

However, 30% improvement in survival for ovarian cancer patients is really dramatic. [edited by moderator]

[sticky3006]

Yes this is interesting and there seems to have been a lot of research into aspirin and non-steroidal anti inflammatories too. Thank you

[ElayneZ in reply to sticky3006]

Curious - would this be referencing Tylenol or more similar to Advil?

[gmc920 in reply to ElayneZ]

Hi, this would be referencing aspirin or non-steroidal anti-inflammatories (which would include Advil/ibuprofen). Not Tylenol/acetaminophen, which is a pain reliever/fever reducer, but is not an anti-inflammatory.

[ElayneZ in reply to gmc920]

Thank you!

[Petrolhead]

A lady who occasionally posts on here - DrDo. (Eileen) a retired GP in Scotland has stated the Ibuprofen she takes has prevented a recurrence.

It is so difficult to prove such stuff without balanced trials. I suspect when looking retrospectively at large numbers of cases a correlation that is statistically significant could be found for a few things.

It is good that researchers are continuing to look at different ways of treating OC and recurrences.

Fay

[IrishMollyO]

Hi there

This subject has come up before and Dr du a retired GP Eileen has posted a lot about it on this site . I followed her as it made a lot of sense to me. Like many people I was prescribed 75mg of Aspirin years ago to prevent strokes . It didn’t obviously prevent my stage 3c PPC but I did wonder if it explained the long intervals between recurrence. My first recurrence was after 5 years. Apart from an unrelated Breast cancer diagnosis last Dec I was given my second recurrence diagnosis last week for PPC after an interval of over two years this time. For me I am happy to still take my aspirin hoping it is fulfilling a duel role. You could search for this lady’s many posts on the subject. Of course if anybody is considering this they should run it by their GP or medical team. Thanks for putting up the link. Take care

XXX

[Luci22 in reply to IrishMollyO]

Thanks for sharing your journey. How many tables would this come to in a day? Is your 75mg in 1 tablet? I don't take it, it's for my mom but I'm not sure if she's taking 75mg.

[IrishMollyO in reply to Luci22]

Hi Luci

I get mine on prescription for the reasons I gave in my original reply. It’s one 75mg a day and they come in that strength. As far as I am aware they can’t be bought over the counter but in any case it would be best if your mum would run this by her GP or medical team . There could be other reasons they don’t suit her so it’s better to be safe than sorry. You could also read Drdu on tbe subject as she has written quite a lot about it on the forum . She is a retired GP and very helpful . I really wish your mum all the best. It’s great that she has you to research information . Take care

XXX

💚💕

[Luci22 in reply to IrishMollyO]

Oh thank you, I am very involved in helping her. I think she's taking the baby aspirin 81mg "daily low dose", which is sold over the counter here in Canada. Would that be similar? All the dosages and types are a bit confusing.

[IrishMollyO in reply to Luci22]

Hi Luci

I’m not good on dosages etc but I think a pharmicist would definitely answer that for you or your mums doctor . Did she start taking them after reading about it here or was she advised for another reason ? For me if I hadn’t been on them for a different reason before I started them. They do thin the blood and stop clotting which is why they are prescribed to prevent strokes. If I can help in any other way let me know . Take care

XXX

💚💕

[Luci22 in reply to IrishMollyO]

I got her on it after reading about it from here, from DrDu. We first spoke to her GP and he increased her stomach medication to protect it. She started about a month after finishing first line treatment and has been on it since. Hopefully it's doing her good. Thanks for your help!

[IrishMollyO in reply to Luci22]

Luci

I’m so delighted that her GP is happy for her to take it . Since I last replied I had a look at dosages etc and it would appear that the common low dose in the US is 81mgs and the same probably applies to Canada . In the UK and Ireland the more common one is 75mgs . Aspirin taken for pain would be over 300mgs and would be really dangerous if taken regularly . I didn’t know that myself until I looked it up just now. You learn something new every day ! Meanwhile best wishes to your mother,and let us know how she gets on. Take care

XXX

💚💕

[IrishMollyO in reply to Luci22]

Sorry for typo. I meant if I hadn’t been on them for a different reason I would definitely have asked my doctor !

[Numi]

As someone else has said, it can't be taken with some treatments. I'm on Niraparib, which could be a game-changer for many of us, but aspirin is one drug that the manufacturer's information specifically says must not be taken whilst on it.

[Yoshbosh]

I started taking low dose aspirin around 6 months after finishing chemo, and it was around the same time that things started to go wrong for me. I went to see a kinesiologist who tested all my medicines and supplements on me, and at the end she had put three things to one side: low dose aspirin, atorvastatin and resveratrol. She looked me in the eye and said I must never take any of them again because they were testing as harmful to me 😳😳😳

Very disappointing as I read such good stuff about aspirin and cancer all the time!

[Di16]

I was told once by a lady on here - Drdu I believe - that low dose Aspirin may help to prevent a recurrence, but wouldn't help if I already got a recurrence. DI

[Solange]

Sorry, I'm rather behind with reading posts but really interested in your article. Thank you for posting it. In November It will be 12 years since I was diagnosed with Ov Ca. I didn't expect to live very long at all, probably a few months. I'm so lucky, despite being on Chemo again for my third recurrence. I've often wondered whether the fact I was already taking a 75mg aspirin tablet daily when diagnosed has anything to do with me making (almost) 12 years. I should point out, though, that I am also prescribed a daily Omeprazole tablet to protect my stomach. This is something Dr Du also recommends people should have.

Best wishes, Solange 😊

[drdu]

Hi Worried Husband.

I just posted re the article in the Lancet which you have referenced in this post. Please see my post. Thank you for giving this link. The article is very interesting. I feel USA is far more on the ball re aspirin and non-steroidal anti-inflammatories (NSAIDs) like ibuprofen as anti-cancer drugs than oncologists in UK are, though there is a large trial involving aspirin being done by cancer research UK, but not in ovarian cancer patients.

Solange's story above is very interesting, and so is mine. I am amazed by what has happened to me by taking ibuprofen. I thought I would have died years ago. Please see my previous posts. I am the drdu mentioned above, a retired GP, and was diagnosed in 2009. My consultant is not convinced re ibuprofen, but it is blindingly obvious to me from my own experience. It is a complicated tale, so please look at my previous posts or my summary (or whatever it is caused). Just click on drdu.

Best wishes.

Eileen