ARIEL 4

[2mini2]

Hi lovely ladies

I just wanted a general consensus on how you were treated for second recurrence?

Im classed as platinum resistant.

I have also been offered ARIEL 4 - anyone on this and drawn the rucaparib arm - how are you doing on it ?

[Yoshbosh]

I know someone on rucaparib and she’s doing OK. I believe she’s stable/had some improvements. I think the drug is showing some promise, but I don’t know much else.

[Nicky100]

Hi 2mini2

I was told that chemo was my only option.

I refused to believe that, so went on a search for something else, I had hoped to find immunotherapy...

I was instead recommended an Oncologist in London for a second opinion.

The rest is history ( on my page). I had a large and radical surgery performed by the fast-becoming-renowned Professor F in London, before then starting chemo.

She has bought me more time. She is incredible and worth you speaking to I think.

I’m not sure on trials but can put you in touch with the same London Oncologist who referred me. He is absolutely up there with all trials.

Good luck,

Nicky

[thomas62 in reply to Nicky100]

Hi Nicky,

Like you Nicky I had surgery in London and was told not a cure but will give more time. And like you Nicky ( and many others here) I am trying to be aware of other treatments, surgeries and trials which may help. Yes immunotherapy appears to be the future; there was a discussion on today's Victoria Derbyshire programme BBC2 about this. Could you please pm me with the info. on the London Oncologist and just how much uptodate info. he has. I am a low grader.

Best wishes Nicky.

Gwen xxx

[Nicky100]

Hi Gwen,

The LOC in London are a good starting point.

The link is here.

theloc.com/consultants/dr-j...

Good luck x

[thomas62]

Thanks Nicky. xxx

[AndreeP]

Hi, I also was categorized as platinum resistant. I was given Avastin and it has kept the disease stable for over 6 months with no progression.

[GoldenGourd]

Sorry I have only now seen your post and I hope my reply is not too late to be of use to you.... I am on Ariel4 and am coming up to the end of my second monthly cycle. It has not been as bad as I feared, in fact no real problems. I like the bi-weekly assessments and hope it is working, but my scan n Thursday will say more about that. If it works out I will only need monthly visits to the clinic. Hope this helps and sorry for delay... I don’t always check in.

Take care and good luck

Netti xxx