Hi, this is my first post, though I've been reading and visiting this site for a couple of months now. My mom has Ovarian cancer, Stage IV since August 2015, and finished her chemo in February, and has was stated to be NED, her CA-125 had dropped down to a 3, from a high of over 3,000 when first diagnosed.
She has been getting Avastin as maintenance therapy for the last 9 months or so, every 3 weeks, and has been tolerating it very well (just slight hypertension). Only in the last month or two am I seeing some odd changes on he lab results. Most prominent is her eosinophils, which have been steadily climbing up. Normal range is 0-0.5, and as of yesterday it was a 3.7. Additionally, her White Blood Counts are very high as well at 12.2.
At the same time, her CA-125 has been slowly creeping up, it stayed at 3 for a while, then went to 4, then 5, then 7, 8, and yesterday a 10. Still quite a low number, but it has doubled in 2 months time. She did have a CT scan in August, and was again NED.
Her doctor scheduled her for a PET / CT scan for this upcoming Tuesday, but I've just wondering if anyone else out there has had elevated eosinophils (and/or WBC count) like this, and if it's related to a recurrence or not. From research, I know that ovarian cancer tumors can elevate eosinophils, though it didn't happen when she was first dx'd, and I haven't really found many discussions about this. I so want it to just be an allergic reaction, or parasites, which is the common cause of high eosinophils.