PPI,s And side effects

Hi All would just like to know how long people on here have been on PPI,s and what dosage and if anyone has had any long term side effects.I,ve been on them for over 5 years and worried about effects especially when you read the paper you get with the pills which says you should,nt be on them longer than 12 weeks.Any replies would be welcome as I suppose more than me would like to know.Thank you.

[Karjade]

I have been on Lanzaprazole for one year. I have Barrett's Oesophagus and I have to take PPI's so I have no choice. I do worry about the side effects but the only thing I have noticed since I have been on Lanzaprazole is tingling in my feet and hands which according to the leaflet could be a rare side effect. However my doctor said he doubts whether it is the Lanzaprazole!

[Hidden in reply to Karjade]

Thanks Karjade for your reply.

[Ruqys in reply to Karjade]

U am suffering from oesophagitis grade B. Is there anything I can do to avoid barrettes.

Thankyou

[Karjade in reply to Ruqys]

Hi. I am on lanzaprazol which helps with the acid which in turn helps if you have Barretts. I have a hiatus hernia as well. There are no symptoms for Barrett's and the only way you know you have it is by having an endoscopy and biopsies. I am now having an endoscopy every three years. I presume you have had an endoscopy and they would have seen if you have Barrett's xxx

[Ruqys in reply to Karjade]

Yes I am having endoscopy after every 2 or 3 years everytime they find oesophagitis grade B inspite of taking pantoprazole 20 sometimes 40, no barrets. Your suggestion is to have lanzoperazole to avoid barrettes

[Karjade in reply to Ruqys]

As long as you are having regular endoscopes and taking your PPI's you are doing the best you can. Just eat foods that do not give you acid which is trial and error. Good luck xxx

[Ruqys in reply to Karjade]

Thank you very much

[DavidP]

I've been on lansoprazole 30mg once daily for 5 years - no problems at all.

[Hidden in reply to DavidP]

Thanks DavidP for your reply

[phil in reply to Hidden]

I have been on a PPI for 4 years 20ml per day .They are generally a very safe drug and my consultant has patients you have been on them for 25 years.

As far as I'm concerned it's about quality of life and I know it's much worst when I come off them with reflux problems..There is a lot of studies on the effects of PPIs but so far the evidence has been suspect I would personally not worry as you are only taking low dose and will definitely help with the Barretts by protecting your Oesophagus from reflux

Phil

[Hidden in reply to phil]

Thanks for your reply Phil all the best

[steve5711]

Hi. I 40mg of Omeperzole, two twice a dad. I do get slight headaches, nothing serious though. Been on them for 9 years. Also have Barratts. Have tried other meds, but they didn't work as well.

[Mary-intussuception in reply to steve5711]

Steve5711

Have you considered asking your GP to change your PPI to Lansoprazole because of the headaches? (Zoton best in my opinion).

This was afffective for a relative of mine. Whilst staying with me (long time ago) she was admitted to my local hospital. It was a doctor there who changed the PPI. He said the lansoprazole was a more "recent drug, with less side effects".

[Hidden]

Thanks for your reply steve.

[lynnbibb]

My husband also suffwered Barrets, and grade 3 O/C, so should be on them. Sadly he has had an allergic reaction to them with blisters/sores and swellings in hs mouth, and a complete change of taste so even saliva was tasting of salt. The hospital have taken him off them, but are at a bit of a loss as to an alternative, so at the mment he is only on Renitadene and Gaviscon.

[Hidden in reply to lynnbibb]

Thanks for your reply lynnbibb,hope your husband is soon sorted,there are other types of antacids apart from PPI,s such as Ranitidine which work differently.All the best

[tallbear]

I am on Lanzoprazole and have been for two years, I was on 30Mg twice a day but I gradually cut it down until I am now on 1 30Mg once a day. They are quite easy to break in half and so

I did one and a half a day for a while, and then cut it down to one. My target is to get down to a half a tablet a day. The long term use is not a great idea.

I have to go for an endoscopy next weekend and they said I must be off of Lanzoprazole for at least a week before, so I am going without and just sucking one Gaviscon advance when I go to bed. No problems so far.

I should explain, I was a Barretts sufferer, I wish I had been prescribed when I had Barretts, because I wasn't prescribed anything for it and it became cancer of the oesophagus and I had to have an Ivor Lewis two part oesophagectomy. Which is in truth hellish.

My advice would be if it stops your reflux keep taking it, but if you can reduce the dose without ill effect do it gradually until you reach the minimum dose which is comfortable for you. Also make sure you aren't sleeping flat, sleep in a propped up position it makes a massive difference to reflux.

And most important of all Good Luck and fingers crossed it doesn't progress.

[tallbear in reply to tallbear]

Oh and sorry I forget to say, I also suffered from the tingling of the feet and it reduced as I reduced my dosage.

[Hidden in reply to tallbear]

Thanks tallbear for your reply all the best.

[Hather]

I have been on Omaprazole for a long time had three endoscopies over those years, the last one bout two years ago said there was no inflammation then ...told by Consultant to carry on

Imhave not noticed any side effects as such except when I had a Dexa Bone scan they said I had oseoporosis and osteopenia. And these tables can sometimes effect the bone density. ..maybe tho because of my age?

However I am 82 and the Omaprazole has definitely helped over the years but I never knew that it can effect the bones..., but I still take them but not every day now ..and I certainly would continue as prescribed if I I had Barrett’s, to be honest at my age I am more concerned about keeping my gut healthy...I have been prescribed Vit D3 for my bones, and try to eat things like salmon etc to help my bones.

Had I realised earlier I would have made sure I ate more food particularly good for my bones.. truly they are not that bad thankfully

I have no medical knowledge but looking after oesophageal problems I think is really so important.

HAther

[Hidden in reply to Hather]

Thanks Hather for your reply,keep well all the best.

[Brenda453]

Ive been on PPI'S for 19 years no side effects at all and at times I've been prescribed up to 90mg.

[4optimistic in reply to Brenda453]

Hi Brenda Hope you are keeping well. May I ask you what brand of PPI you are on. I am on Pantoprazole, 80gm petr day plus 300 Ranitidine without much success but thinking of changing to Lansoprazole.

Best wishes

[Brenda453]

Hi im on 40mg Esomeprazole twice daily I also take 10mls Malox suspension at night before bed I find the Botox injections work very well I have 5 areas of my Oesophagus done ever 6 to 9 months

[Ruqys in reply to Brenda453]

What is malox and botox