I was diagnosed about 6 months ago. The pain in the knees was horrible. I feel it is traveling to my ankles as well. Does it move to various joints in time? I am taking 8 methotrexate by injection and 2 plaqunil a day. I had gastritis bypass over 15 years ago so I wasn't absorbing the methotrexate. I feel like the methotrexate is beginning to not work as the pain is back . Is is a trial and error game for many years to come? I also was getting steroid shots in the knees about every other month. It absolutely wears me out.