Methotrexate and Meloxicam: I have been on methotrexate... - NRAS

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Methotrexate and Meloxicam

jayne17 profile image
12 Replies

I have been on methotrexate for a long long time (now injected), probably 20 years and also anti inflammatory Meloxicam for as long as I can remember. However today my GP surgery called me to do a medication review and said I shouldn't be taking the 2 together as it wasn't safe. I take the Meloxicam 7.5mg as and when I need it which probably equates to about 2/3 times a week. They would be removing this from my prescribed medication and replacing it an topical gel. Is this right and has anyone else had any experience of this. Any comments please.

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12 Replies
Boxerlady profile image
Boxerlady

Was the Meloxicam originally prescribed by your rheumatology team? If so, I'd contact them as GP surgeries don't have much experience of Methotrexate and can sometimes misunderstand the prescribing issues.

jayne17 profile image
jayne17 in reply toBoxerlady

Yes I will be speaking to rheumatology nurse soon and will check with them. Thanks for your reply.

Seatgeorge profile image
Seatgeorge

Speak to the RA nurse they have a much greater knowledge than most Gp's.The local pharmacist probably will have a much better understanding on the drugs they issue, good luck

oldtimer2 profile image
oldtimer2

This is an automatic response from the GP surgery. You are over 65 years, according to their guidelines you should avoid NSAIDs (Non-steroidal Anti-Inflammatory Drugs ) of which meloxicam is one. This is because the risks of taking NSAIDs increase with age. They did the same to me some years ago.

You need a discussion with your rheumy team about your pain relief and then they can advise your surgery on what is the best option.

jayne17 profile image
jayne17 in reply tooldtimer2

Thanks for your reply, I will be talking to my rheumatoid nurse soon.

ranne21 profile image
ranne21

It’s tricky isn’t it. I take Methotrexate too and was put on Meloxicam daily for about three months when my RA got out of control. The consultant expressly said it was fine to take the two together but two pharmacists plus my own research indicated otherwise. I’ve booked a call with my (good) GP as I will need it again soon and want to discuss things properly first!

jayne17 profile image
jayne17 in reply toranne21

Yes it is. Everyone is covering their own backs in everything we do. They point out the side effects and leave it to you. Nobody wants to advise. Thanks for your reply, I shall speak to the RA nurse soon

Wobbies profile image
Wobbies

My GP prescribes meloxicam and MTX as advised by the consultant. I have even queried it with him but he says all painkillers have side effects and he has nothing more effective than Meloxicam for me.

jayne17 profile image
jayne17 in reply toWobbies

Thats good to hear, yes I suppose all meds have side effects of some sort. Thanks for your reply.

LindaDee profile image
LindaDee

I was taken off Ibuprofen which is a NSAID like Meloxicam due to my age and I’m 68. I think it’s unfortunate because it is the only medication that helps at all.

jocascanet profile image
jocascanet

Yes, all drugs have side effects especially the biologics. Methotrexate caused a soft tissue necrosis in radiated breast tissue several years ago. The NSAIDs can cause heart issues including BP issues. Actemra which I am currently on has a long list of possible complications. We just have to select what works best for us and go for it.

jayne17 profile image
jayne17 in reply tojocascanet

Yes we do, its just after being on these for 20 years or more I would have thought they could have brought it to me attention before. But I expect its a risk we are willing to take if they get us through the effects of RA. Thanks for replying.

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