Sulfasalazine: Hi Question, Is anyone else on... - NRAS

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Sulfasalazine

Lunar246 profile image
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Hi Question, Is anyone else on Methotrexate and sulfasalazine? I spoke to my rheumatologist about my pain going back to the way it was before the methotrexate since I came off the prednisolone, so he gave me another 5 week course of prednisolone and put me on sulfasalazine to anyone who's also on it any good?

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Lunar246 profile image
Lunar246
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helixhelix profile image
helixhelix

I was on it for around 8 years. Same as you started just with MTX and then it was added in (and then hydroxy a bit later). It worked.

For the first couple of months my stomach was quite ‘excitable’, but that calmed down. Only long term side effect was bright orange pee..

Boxerlady profile image
Boxerlady

I've been on Methotrexate and Hydroxychloroquine since May/June 2019 and although there were improvements things weren't great and actually got worse late spring. I was put on Metoject and titrated up to the maximum dose (25mg) but still not "right" so Sulfasalazine was added (4 tablets a day) and it made a real difference. Last week (after a couple of months on Sulphasalazine) my dose was increased to 5 tablets a day and I can already see a slight improvement so for me (and as we all know, we're all different!) the addition of Sulphasalazine was the game changer. Initial mild side effects but only the impressive orange pee is the permanent one 😁

Summerrain14 profile image
Summerrain14

I am on MTX and Sulphasalzine. I started off on Sulphasalzine and MTX added in. I have no issues at all with Sulphasalzine. When I first started it I did have some mild side effects with feeling a little out of it and no appetite but that soon settled. You start of with loading doses but I noticed working 9 weeks or so it had started working for me. Fingers crossed it helps you too. x

SFZ gave me tinnitus. I gave it up. Still have the tinnitus 18 months later.

Sharon56 profile image
Sharon56

Hi I've been on Sulphasalazine for about 10 years maybe longer. For the last 8 years I've been on methotrexate by injection. Previous to that I was on the tablet form of methotrexate l.

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