I'm not sure that being sero-negative or sero-positive is actually much help with management options. It's more a question of keeping the inflammatory markers in normal (for you) ranges and being as symptom and sign free as possible.
It's such a diverse illness that perhaps each individual needs their own measurements of success, until the research is able to sort us out into categories depending on which bit of our very complicated immune system is out-of-order.
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