Hi, I have been living reasonably well with RA for 3 years now and on Humira this last year with positive impact but developed really bad acid reflux & IBS symptoms in the summer. Diet has been radically improved so IBS greatly reduced; exercise is difficult given state of my joints but slowly losing weight. So doing all the right things but acid reflux still bad--all tests show no organic cause; slight inflammation of the duodenum but no infection, bacterial imbalance, coeliac etc. Specialist nurse taken me off Humira as it is possibly the culprit a week ago and I am feeling completely fatigued already. Any advice or ideas? Is it normal to be so fatigued just 1 week into no treatment and any ideas re the acid reflux?