Quercetin for rheumatoid arthritis

[MickeyJoints]

This study has been bought to my attention and I thought I'd share it with everyone.

The test sample were all women and given the incidence of RA in women, the study organisers were going to get a pool of subjects more easily.

"The phytonutrient and dietary supplement quercetin has been shown to lower disease activity and reduce clinical symptoms in women with rheumatoid arthritis."

Might be worth a go perhaps...

timeforwellness.org/blog-vi...

It's a double blind randomised trial with a link off to PubMed to the original study.

MJ

[oldtimer]

Thanks for the information and the link.

[Matilda7]

Very small sample...only 50 women split into 2 groups and have only seen the abstract not the full paper, so can't judge the quality.

[MickeyJoints in reply to Matilda7]

Agreed, but so rare to find some rigorous research for this topic that is not anecdotal in structure.

[Don122 in reply to MickeyJoints]

Rigorous? How do you know? Preliminary studies are notorious for subtle biases in favor of treatment. The abstract does not give amounts of clinical improvement over placebo. Statistical significance does not mean clinically relevant.

[MickeyJoints in reply to Don122]

Compared to 100 people saying "[treatment] is fantastic, 'cos it cured me. " That kind of thing.

Quite right, I've not seen the method used in the trial so cannot absolutely say that it's rigorous, just that it's reported to be double blind and randomised.

Agreed, stats don't mean an effect clinically.

[MickeyJoints in reply to Don122]

Full text:

ncbi.nlm.nih.gov/pmc/articl...

[Don122 in reply to MickeyJoints]

Quite true that its better than anecdotes. Interestingly the study you linked to is a set of different (and negative) results. My point is that no one should be running out to buy this products just yet.

[MickeyJoints in reply to Don122]

Thanks Don,

As I said, I'd not read it yet :shame-face:

Seems it was exactly the same authors from the same university but the study was for a different purpose. Seems second study was looking at adverse effects of quercetin might have on BP and other stress markers:

"... the present study examined the effects of bioflavonoid quercetin on total antioxidant capacity (TAC) of plasma, lipid peroxidation and blood pressure in women with RA"

So not as the first study, which was looking at "We investigated the effect of quercetin supplementation on inflammation, disease severity, and clinical symptoms in women with rheumatoid arthritis"

I think the second study is saying that quercetin is not going to have bad effects on you, thus no difference to the placebo group. Is that how you read it?

Where as the first was saying it appears to have some positive effect.

Thanks for pointing that out. If I could just find a full text version...

[Hidden]

Excellent find MJ. Thanks for posting

[woodstar1]

Great find, I'll definitely have a look at trying some of this, thanks.

[Gigi71]

Have signed up to the sister, thanks for posting.

[Gigi71 in reply to Gigi71]

What a pain, auto correct put in sister, meant SITE. Lol.

[Hidden]

Hi Mickeyjoints - Interesting results - I'll have to look it up... Thanks!

[MickeyJoints]

FULL TEXT:

ncbi.nlm.nih.gov/pmc/articl...

Thought I'd have a look around and it's on that link. I've not read it yet and I have no involvement in the trial so you're on your own!

MJ