I was put on HDC when first diagnosed - couldn't tolerate it - then tried Mex tabs - ill as anything - then Sulph - which I thought I was literally going to die from the side effects. I didn't even get upto the full dose. Never been so poorly in my life!! had a chat with rheumy nurse and decided to give Mex another go but with injections. Worked great for over a year, then rheumatologist increased the dose ( went up to 25mg) and I ended up with five chest infections in 8 months ( including pneumonia) so said NO to anymore Mex despite going right back down on reduced doses. They messed about with the dose for about a year before I finally said enough.
Another discussion with Rheumy and decided to give HDC 200mg another go. The first prescription was from the hospital pharmacy - Plaquenil - which were absolutely fine- no problems at all but after that, I had to get repeat scripts from my chemist. Tried brand name by Quinoric and just could not tolerate it. So they've given me HDC by Zentiva. Managed three weeks with no side effects but now again, side effects are horrible. Fatigue, nausea, diarrhoea - all the usual stuff. I spoke to hospital pharmacy who said that Plaquenil were no longer being manufactured.
I seem to be able to take the Zentiva brand for three days before the side effects hit me really hard so stop them for a week before I try again.
Don't know what to do for the best. I know that my rheumy is starting to despair of me. I just want to be able to tolerate a Dmard or else I'm just going to give up and let this damn disease take control.
Has anyone actually given up a Dmard and been okay?